DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mocs1 and F49H6.5

DIOPT Version :9

Sequence 1:	NP_788494.1	Gene:	Mocs1 / 39238	FlyBaseID:	FBgn0263241	Length:	565	Species:	Drosophila melanogaster
Sequence 2:	NP_001370025.1	Gene:	F49H6.5 / 186073	WormBaseID:	WBGene00009908	Length:	389	Species:	Caenorhabditis elegans

Alignment Length:	383	Identity:	182/383 - (47%)
Similarity:	251/383 - (65%)	Gaps:	43/383 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 ENSAGEVA-------------------SLSRGAIRLKATTGYLNLATASVQPLEPEKQVLRKNSP 60
            ::||||:.                   ...|.|:::|            :|.:|..|..|    |
Worm    16 KSSAGEIVKQLTVPLREHAEPIVLLTPEQKREAVKVK------------IQEIERAKGQL----P 64

  Fly    61 LTDSFGRHHTYLRISLTERCNLRCDYCMPAEGVPLQPKNKLLTTEEILRLARIFVEQGVRKIRLT 125
            ..|.|.|.||||||||||:||.||.|||||||:||:||:|:|:..|:|||.::|...||.|:|||
Worm    65 FFDMFMREHTYLRISLTEKCNFRCLYCMPAEGIPLKPKDKMLSNSEVLRLVKLFAAHGVDKVRLT 129

  Fly   126 GGEPTVRRDIVEIVAQMKALPELEQIGITTNGLVLTRLLLPLQRAGLDNLNISLDTLKRDRFEKI 190
            |||||:|.|:|:||..:.:.|.::::|||||||||.|.|..|:.|||..:|||:|:|.|::|.|:
Worm   130 GGEPTIRNDLVQIVEGISSTPGIKEVGITTNGLVLPRFLPKLKDAGLTKINISIDSLDREKFAKM 194

  Fly   191 TRRKGWERVIAGIDLAVQLGYRPKV--NCVLMRDFNEDEICDFVEFTRNRPVDVRFIEYMPFSGN 253
            |||.|:::|...|:||  .||.|||  |.|:::..||:||.|||..|:.|.:|:||||:|||.||
Worm   195 TRRDGFDKVWKAIELA--RGYFPKVKLNVVVLKHQNENEIVDFVNLTKGRNLDIRFIEFMPFGGN 257

  Fly   254 KWHTERLISYKDTLQIIRQRWPD-FKALPNGPNDTSKAYAVPGFKGQVGFITSMTEHFCGTCNRL 317
            ::..:..:||::.|.:|..::.| ...|.:.||||:|||.:.||:||.||||||::|||.|||||
Worm   258 EFKNDSFMSYREMLNLIVDKYGDAVIRLSDLPNDTTKAYKIDGFQGQFGFITSMSDHFCNTCNRL 322

  Fly   318 RLTADGNIKVCLFGNKEFSLRDAMRDESVSEEQLVDLIGAAVQRKKKQHA--DAAPRL 373
            |:|||||:||||.||.|.||||.:|... |:.:|.::|..||..||.:||  ||...|
Worm   323 RITADGNLKVCLHGNSEVSLRDRIRCGD-SDAKLSEVIQTAVDNKKARHAGMDALKNL 379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mocs1	NP_788494.1	moaA	59..366	CDD:234672	166/309 (54%)
		Radical_SAM	74..249	CDD:100105	96/176 (55%)
		Mob_synth_C	240..367	CDD:283994	66/127 (52%)
		moaC	399..555	CDD:236483
F49H6.5	NP_001370025.1	PLN02951	67..389	CDD:215513	170/316 (54%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167342
Domainoid	1	1.000	181	1.000	Domainoid score	I2068
eggNOG	1	0.900	-	-		E1_COG2896
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4343
Inparanoid	1	1.050	475	1.000	Inparanoid score	I819
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D337398at33208
OrthoFinder	1	1.000	-	-		FOG0005129
OrthoInspector	1	1.000	-	-		otm14715
orthoMCL	1	0.900	-	-		OOG6_101306
Panther	1	1.100	-	-	O	PTHR22960
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4665
SonicParanoid	1	1.000	-	-		X3650
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790