Protein Alignment CG6321 and KYAT1

DIOPT Version :10

• Sequence 1: NP_648426.1
• Gene: CG6321 / 39233
• FlyBaseID: FBgn0036117
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_001274319.1
• Gene: KYAT1 / 883
• HGNCID: 1564
• Length: 516
• Species: Homo sapiens
• Alignment Length: 464
• Identity: 98/464 - (21%)
• Similarity: 170/464 - (36%)
• Gaps: 120/464 - (25%)

  Fly     1 MLKSSQDRKLKHLFDGGDWNVYAP--------NILNLGVGAPG---PDILTANCDSFRTATDHCL 54
            |.|..|.|:|    ||.|:|.:..        :::|||.|.|.   ||...   ::|:.|.
Human    95 MAKQLQARRL----DGIDYNPWVEFVKLASEHDVVNLGQGFPDFPPPDFAV---EAFQHAV---- 148

  Fly    55 EREKRENQSLIFQYGPTSGTFEVRREISTYFTEMFKSPVN-CEDLIITTGASHGLHILLSTMLDF 118
                 ....::.||..|.|...:.:.::::|.|:....:: ..::::|.|....|......::|
Human   149 -----SGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGYGALFTAFQALVD- 207

  Fly   119 EG------FVFVDEYTYMIALDSIKH-FSTVTIVPVKLNDDG------VDLKDLEEKVSKRRFQS 170
            ||      ..|.|.|..|..:...:. |.::...|::..:.|      :|..:|..|     |.|
Human   208 EGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGK-----FTS 267

  Fly   171 KKKEFWGIYYTIPTYHNPTGILFSPEVCRGIVQLARNYDFLVVCDDVYNILNYGETPTHSRLLSY 235
            :.|..     .:.|.:||.|.:||.|....:..|.:.:|.:.:.|:||            :.:.|
Human   268 RTKAL-----VLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVY------------QWMVY 315

  Fly   236 DDRNDANFAG------HVISNGSFSKIL-GPGVRLGWL----EVPPRLKPILDGSGFATSGGCFN 289
            |.....:.|.      ..::.||..|.. ..|.::||:    .:...|:.:...|.|    .|..
Human   316 DGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPDHIMKHLRTVHQNSVF----HCPT 376

  Fly   290 NYTSGIVGSLFELKLAQKQISESYEAYKERMLATTQVLRDELPDC-----CKLVSPTGGYFIWVR 349
            ...:.:..|....:|..:|.|..:..:.:.|    |..||.:...     .|.:.|.|.||:...
Human   377 QSQAAVAESFEREQLLFRQPSSYFVQFPQAM----QRCRDHMIRSLQSVGLKPIIPQGSYFLITD 437

  Fly   350 I----------PDRLD---CREFLKYCMENHKIYFIVGTRFSADGQSGKQFFRLSIAFY--PKSK 399
            |          |..:|   .|.|:|:.::|                .|.....:|| ||  |..|
Human   438 ISDFKRKMPDLPGAVDEPYDRRFVKWMIKN----------------KGLVAIPVSI-FYSVPHQK 485

  Fly   400 LVDGARRLC 408
            ..|...|.|
Human   486 HFDHYIRFC 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6321	NP_648426.1	ARO8	<23..414	CDD:440781	89/442 (20%)
KYAT1	NP_001274319.1	AspB	101..512	CDD:440205	95/458 (21%)