DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6321 and SPBC1773.13

DIOPT Version :9

Sequence 1:	NP_648426.1	Gene:	CG6321 / 39233	FlyBaseID:	FBgn0036117	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_595128.1	Gene:	SPBC1773.13 / 2540092	PomBaseID:	SPBC1773.13	Length:	481	Species:	Schizosaccharomyces pombe

Alignment Length:	413	Identity:	98/413 - (23%)
Similarity:	157/413 - (38%)	Gaps:	96/413 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 NQSLIFQYGPTSGTFEVRREISTYFTEMFKSPVNCEDLIITTGASHGLHILLSTMLDFEGFVFVD 125
            :|||  |||...|..|:...|..:...:........|:.::.|.:.||...|..::::...|..:
pombe    95 SQSL--QYGQCQGISELVGFIKEHIRRIHAPRYENWDIKMSNGNTSGLEYCLRLLVNYGDHVLTE 157

  Fly   126 EYTYMIALDSIKHFSTVTIVPVKLNDDGVDLKDLEEKVSKRRFQSKKKEFWGI--------YYTI 182
            :|||..|:.:::... |..|.|.::.:|:..:.|||.:..          |.|        .||:
pombe   158 KYTYPAAITAMRALG-VQFVSVDMDSEGMLPESLEEIMRD----------WDISLGPRPHVLYTV 211

  Fly   183 PTYHNPTGILFSPEVCRGIVQLARNYDFLVVCDDVYNIL-----NYGETPTHSR----------- 231
            ||..||||...|....:.::.|||.||.::|.|:.|..|     |....|...:
pombe   212 PTGQNPTGSTLSLSRRKKLLALARKYDIIIVEDEPYYFLQMEDYNGSLNPAQQKCDGSTFLKSLV 276

  Fly   232 --LLSYDDRNDANFAGHVISNGSFSKILGPGVRLGWLEVPPRLKPILDGSGFATSGGCFNNY--- 291
              |||.|..      |.|:...||||::.||.|||::                |....|.::
pombe   277 PSLLSLDTE------GRVLRLDSFSKLIAPGTRLGYI----------------TGNSMFIDHITR 319

  Fly   292 --------TSGIVGSLFELKLAQ-------KQISESYEAYKERMLATTQVLRDELPD-CCKLVSP 340
                    .|||..|:....|..       ..:.|...:|..|..|...|....||: .|....|
pombe   320 IAEVCTESPSGICQSVLYAMLHNWGQEGFCAWLQELQYSYTVRRNAFLNVANKYLPNSVCIYHVP 384

  Fly   341 TGGYFIWV-------RIPD------RLDCREFLKYCMENHKIYFIVGTRFSADGQ-SGKQFFRLS 391
            ..|.|:||       |..|      :::...||....:..|.  :.|..|.|:.: |.|.|||.:
pombe   385 RAGLFLWVELNLNHYRFSDTKKSVSQIEMEIFLALVEKGVKT--VCGQFFMANPERSTKIFFRFA 447

  Fly   392 IAFYPKSKLVDGARRLCNALKDY 414
            .:........:|.:|..:.:.::
pombe   448 YSIADFEDFEEGIKRFTSVINEH 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6321	NP_648426.1	AspB	25..414	CDD:223513	98/411 (24%)
CG6321	NP_648426.1	AAT_like	27..407	CDD:99734	97/404 (24%)
SPBC1773.13	NP_595128.1	Aminotran_1_2	91..463	CDD:278580	97/404 (24%)
SPBC1773.13	NP_595128.1	AAT_like	98..463	CDD:99734	95/401 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	79	1.000	Domainoid score	I2353
eggNOG	1	0.900	-	-		E1_COG1167
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	85	1.000	Inparanoid score	I1796
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002460
OrthoInspector	1	1.000	-	-		otm47391
orthoMCL	1	0.900	-	-		OOG6_100686
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R7
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.790