DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6321 and Aadat

DIOPT Version :9

Sequence 1:	NP_648426.1	Gene:	CG6321 / 39233	FlyBaseID:	FBgn0036117	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	XP_006509460.1	Gene:	Aadat / 23923	MGIID:	1345167	Length:	442	Species:	Mus musculus

Alignment Length:	401	Identity:	95/401 - (23%)
Similarity:	171/401 - (42%)	Gaps:	56/401 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 AP-NILNLGVGAPGPDILTANCDSFRTATDHCLEREKRENQSLI----------FQYGPTSGTFE 76
            || .:::|..|:|.|.:......:|..           ||.|.|          .||.|:.|..|
Mouse    29 APKTLISLAPGSPNPSMFPFKSAAFTV-----------ENGSTIRFEDDLIKRALQYSPSYGIPE 82

  Fly    77 VRREISTYFTEMFKSP-VNCE------DLIITTGASHGLHILLSTMLDFEGFVFVDEYTYMIALD 134
            :...:..:..::...| ||..      ||.||:|...||......:::....:.|:|..:...|.
Mouse    83 LLSWLKQFQVKLHNPPTVNYPPNQGQMDLCITSGCQDGLCKAFEMLINPGDTILVNEPLFPGTLY 147

  Fly   135 SIKHFSTVTIVPVKLNDDGVDLKDLEEKVSKRRFQSKK---KEFWGIYYTIPTYHNPTGILFSPE 196
            ::|... ..|:.|..::.|:..:.|::.:|:.:.:..|   |:.....||:|..:||||...:.:
Mouse   148 AMKPLG-CNIINVPSDEHGIIPEGLKKILSQWKPEDSKDPTKKTPKFLYTVPNGNNPTGNSLTGD 211

  Fly   197 VCRGIVQLARNYDFLVVCDDVYNILNYGETPTHSRLLSYDDRNDANFAGHVISNGSFSKILGPGV 261
            ..:.|.:|||.||||::.||.|..|.:.: |.....||.|      ..|.||...:|||.:..|:
Mouse   212 RKKEIYELARKYDFLIIEDDPYYFLQFSK-PWEPTFLSMD------VDGRVIRADTFSKTVSSGL 269

  Fly   262 RLGWLEVPPRL-KPILDGSGFATSGGCFNNYTSGIVGSLFELKLAQKQISESYEAYKERMLATTQ 325
            |:|::..|..| :.|:..:..::...|       .:..|..|:|..:...|.:.|:.:|.:...:
Mouse   270 RVGFMTGPKTLIQNIVLHTQVSSVHAC-------TLSQLMILQLLHQWGEEGFLAHIDRTIDFYK 327

  Fly   326 VLRDE--------LPDCCKLVSPTGGYFIWVRIPDRLDCREFLKYCMENHKIYFIVGTRFSADGQ 382
            ..||.        |....:...|..|.|:|:::....|.::.::......::..:.|..|..||.
Mouse   328 NQRDSILAAADKWLRGLAEWHVPKAGMFLWIKVKGISDTKQLIEEKAIEREVLLVPGNGFFIDGS 392

  Fly   383 SGKQFFRLSIA 393
            :...|||.|.:
Mouse   393 APTSFFRASFS 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6321	NP_648426.1	AspB	25..414	CDD:223513	93/398 (23%)
CG6321	NP_648426.1	AAT_like	27..407	CDD:99734	93/396 (23%)
Aadat	XP_006509460.1	ARO8	16..412	CDD:224089	95/401 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	87	1.000	Domainoid score	I8052
eggNOG	1	0.900	-	-		E1_COG1167
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	96	1.000	Inparanoid score	I5040
Isobase	1	0.950	-	0.910401	Normalized mean entropy	S3036
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002460
OrthoInspector	1	1.000	-	-		oto94972
orthoMCL	1	0.900	-	-		OOG6_100686
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R7
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.740