DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7888 and AVT6

DIOPT Version :9

Sequence 1:	NP_648425.1	Gene:	CG7888 / 39232	FlyBaseID:	FBgn0036116	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_011044.1	Gene:	AVT6 / 856855	SGDID:	S000000921	Length:	448	Species:	Saccharomyces cerevisiae

Alignment Length:	461	Identity:	87/461 - (18%)
Similarity:	176/461 - (38%)	Gaps:	108/461 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 LLKGSLGTGILAMPNAFRNSGYITGSIGTIVIGFICTFCIHQLVKAQYELCRRKKMPSMNYPMVA 126
            ||..:.|.||||||.||:..|.|.|    :::..:|..|..|.:..|..:.  |.:|.......|
Yeast    12 LLHTACGAGILAMPYAFKPFGLIPG----VIMIVLCGACAMQSLFIQARVA--KYVPQGRASFSA 70

  Fly   127 ETAMGEGPKCFRVFAPYIGTVVNTFLLIYQLGTCCVYVVFVASNIKAIVDA------VADTSIDV 185
            .|         |:..|.:|.|.:..:.|...|....|::.|...:..|:..      :.:.::.:
Yeast    71 LT---------RLINPNLGIVFDLAIAIKCFGVGVSYMIVVGDLMPQIMSVWTRNAWLLNRNVQI 126

  Fly   186 RLCMIIILLPLILINWVRNLKYLAPFSTLANAITMVSFGIICYYIF-------REPVTTEGKDAF 243
            .|.|:..:.||..:..:.:|:|       |:.:.:.|...:|..:.       .|.:..:|:.::
Yeast   127 SLIMLFFVAPLSFLKKLNSLRY-------ASMVAISSVAYLCVLVLLHYVAPSDEILRLKGRISY 184

  Fly   244 GKP---------SNFPLFFGTVLFALEAIGVILPLENEMKTPQKFGGSCGVLNVSMVLIVFLYVG 299
            ..|         :..|:|    :||......:..:.||.:: .:|.....:..:::.|.:.||:.
Yeast   185 LLPPQSHDLNVLNTLPIF----VFAYTCHHNMFSIINEQRS-SRFEHVMKIPLIAISLALILYIA 244

  Fly   300 MGLFGYLNYGSAVLGSITLNMPEHEVLSMCVKGMLAFAIYITHGLACY----------------- 347
            :|..|||.:|..::|:|.:..|: .|.|...:..:...:.:...|.|:
Yeast   245 IGCAGYLTFGDNIIGNIIMLYPQ-AVSSTIGRIAIVLLVMLAFPLQCHPARASIHQILQHFAEEN 308

  Fly   348 VAIDITWND----------------------------YVAKRLGAQRNALFWEYAVRTGLVLITF 384
            |:|..|..|                            |..|....:..:..   .:...:::.::
Yeast   309 VSISATSADEPTVATESSPLIRDSSLDLNEVIEEESIYQPKETPLRGKSFI---VITCSILVASY 370

  Fly   385 LLAVAIPNLELFISLFGALCLSALGLAFPALIQICTHWYNTKGFA-KVWLVLSNFVLIIVGIL-- 446
            |:|:::.:|...:::.||...:::....|.|.     .|...|.. |..:.|:..:....|:|
Yeast   371 LVAISVSSLARVLAIVGATGSTSISFILPGLF-----GYKLIGTEHKTAVPLTTKIFKYTGLLLF 430

  Fly   447 --GLVI 450
              ||:|
Yeast   431 IWGLII 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7888	NP_648425.1	SLC5-6-like_sbd	51..453	CDD:294310	87/461 (19%)
CG7888	NP_648425.1	SdaC	62..456	CDD:223884	87/461 (19%)
AVT6	NP_011044.1	Aa_trans	1..439	CDD:279788	87/461 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346002
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4217
OMA	1	1.010	-	-		QHG54358
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X121
TreeFam	0	0.000	Not matched by this tool.
	6	5.700