DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7888 and Slc38a10

DIOPT Version :9

Sequence 1:	NP_648425.1	Gene:	CG7888 / 39232	FlyBaseID:	FBgn0036116	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	XP_006534347.1	Gene:	Slc38a10 / 72055	MGIID:	1919305	Length:	1111	Species:	Mus musculus

Alignment Length:	453	Identity:	88/453 - (19%)
Similarity:	162/453 - (35%)	Gaps:	128/453 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 HLLKGSLGTGILAMPNAFRNSGYITGSIGTIVIGFICTFCIHQ----LVKAQYELCRRKKMPSMN 121
            :::...:|..:|.||..|:..|.:   :|.:::.| |::..||    |||:. .|.:|:....:.
Mouse    14 NVVNSIVGVSVLTMPFCFKQCGIV---LGALLLVF-CSWMTHQSCMFLVKSA-SLSKRRTYAGLA 73

  Fly   122 Y-------PMVAETAM-----GE--------GPKCFRVFAPYIGTVVNTFLLIYQLGTCCVYVVF 166
            :       .|:.||:|     |.        |......|||.:|..|...:.::.|....:::|.
Mouse    74 FHAYGKAGKMLVETSMIGLMLGSCITFYVVIGDLGSNFFAPLLGLQVTRTVRVFLLFAVSLFIVL 138

  Fly   167 VASNIKAIVDAVADTSIDVRLCMIIILLPLILIN---------WVRNLKYLAPFSTLANAITMVS 222
            ..|..:.::.::...|....|...:.:..::|.:         |:|.:.|:. :..:...:.:..
Mouse   139 PLSLQRNMMASIQSFSAMALLFYTVFMFVIVLSSLKHGLFSGQWLRQVSYIR-WEGVFRCVPIFG 202

  Fly   223 FGIICYYIFREPVTTEGKDAFGKPSNFPLFFGTVLFALEAIGVILPLENEMKTPQKFGGSCGVLN 287
            ....|     :.......|:..:||                         :||......|
Mouse   203 MSFAC-----QSQVLPTYDSLDEPS-------------------------VKTMSSIFAS----- 232

  Fly   288 VSMVLIVFLYVGMGLFGYLNYGSAVLGSITLNMPEHEVLSMCVKGMLAFAIYITHG-----LACY 347
             |:.::...||.:|.|||:::..|..|::.::.|.:.|..|...|   |.:.:..|     |.|.
Mouse   233 -SLNVVTAFYVMVGFFGYVSFTDATTGNVLIHFPSNPVTEMIRVG---FVMSVAVGFPMMILPCR 293

  Fly   348 VAIDITWNDYVAKRLGAQRNALFWEYAVRTG-------------------LVLITFLLAVAIPNL 393
            .|:                |.|.:|...:.|                   :|..|.:..|.|||:
Mouse   294 QAL----------------NTLLFEQQQKDGTFAAGGYMPPLRFKVLTLSVVFGTMVGGVMIPNV 342

  Fly   394 ELFISLFGALCLSALGLAFPALIQICTHWYNTKGFAKVWLVLSNFVLIIVGILGLVIGTYTSL 456
            |..:...||...|.:....||||....|.........:|          ||:..||:.|.|:|
Mouse   343 ETILGFTGATMGSLICFICPALIYKKAHKNAPSAQVVLW----------VGLGILVVSTLTTL 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7888	NP_648425.1	SLC5-6-like_sbd	51..453	CDD:294310	85/448 (19%)
CG7888	NP_648425.1	SdaC	62..456	CDD:223884	87/450 (19%)
Slc38a10	XP_006534347.1	SLC5-6-like_sbd	6..381	CDD:382020	80/427 (19%)
		PTZ00121	<407..789	CDD:173412
		PTZ00449	<731..>991	CDD:185628
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810