DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7888 and Slc38a4

DIOPT Version :9

Sequence 1:	NP_648425.1	Gene:	CG7888 / 39232	FlyBaseID:	FBgn0036116	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_001344987.1	Gene:	Slc38a4 / 69354	MGIID:	1916604	Length:	547	Species:	Mus musculus

Alignment Length:	535	Identity:	98/535 - (18%)
Similarity:	179/535 - (33%)	Gaps:	164/535 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 NSAYVADHPDKLELAEKGQKNKAVVAKDPDYNPYHHRDVEHPTTNSETLFHLLKGSLGTGILAMP 75
            ||.:..:..:..:....|...|..:|   ||...||..:   |:...:.|:|....:|:|||.:.
Mouse    39 NSQFANEDAESQKFLTNGFLGKKKLA---DYADEHHPGM---TSFGMSSFNLSNAIMGSGILGLS 97

  Fly    76 NAFRNSGYITGSIGTIVIGFICTFCIHQLVKAQYELCRRKKMPSMNYPMVAETAMGEGPKCFRVF 140
            .|..|:|.|...|..:.:..:..:.:|.|:|.      .|:..|:.|..:.|.|.|...|
Mouse    98 YAMANTGIILFIIMLLTVAILSLYSVHLLLKT------AKEGGSLIYEKLGEKAFGWPGK----- 151

  Fly   141 APYIGTVVNTFLLIYQLGTCCVYVVFVASNIKAIVDAVADTSID-----------VRLCMIIILL 194
               ||..::  :.:..:|....|:..:...:..::.|......:           |....:.|:|
Mouse   152 ---IGAFIS--ITMQNIGAMSSYLFIIKYELPEVIRAFMGLEENTGEWYLNGNYLVLFVSVGIIL 211

  Fly   195 PLILINWVRNLKYLAPFSTLANAITMVSFGIICY------------------------------- 228
            ||.|:   :||.||...|..:.:..:....::.|
Mouse   212 PLSLL---KNLGYLGYTSGFSLSCMVFFVSVVIYKKFQIPCPLPALDHNNGNLTFNNTLPIHMIS 273

  Fly   229 ---------------YIFREPVTTEGKDAFG-----------------KPSNFPLFFGTVLFALE 261
                           |....|...:.|...|                 :|..| :|.....:|:.
Mouse   274 LPNDSESSGVNFMMDYAHHNPAGLDEKQVAGPLHSNGVEYEAQGAEKCQPKYF-VFNSRTAYAIP 337

  Fly   262 AIGV-------ILPLENEMKTPQKFGGSCGVLNVSMVLIVFLYVGMGLFGYLN-YGSAVLGSITL 318
            .:..       :||:.:|:|...:..... |.|:|:..::.:|:...|||||: ||..
Mouse   338 ILAFAFVCHPEVLPIYSELKDRSRRKMQT-VSNISISGMLVMYLLAALFGYLSFYGDV------- 394

  Fly   319 NMPEHEVLSMCVKGMLAFAIYITHGLACYVAIDITWNDYVAKRLGAQRNALFWEYAVRTGLVLIT 383
               |.|:|                                        :|....|...|.|:::.
Mouse   395 ---EDELL----------------------------------------HAYSKVYTFDTALLMVR 416

  Fly   384 FLLAVAIPNLELFISLFGALCLSALGLAFPALIQICTHWYNTKGFAKVWLVLSNFVLIIVGILGL 448
            ..:.||: .|.:.|.|| .:..|.:.|.||   :....|....|.|.:.:.|:|.::|:|..:..
Mouse   417 LAVLVAV-TLTVPIVLF-PIRTSVITLLFP---RKPFSWLKHFGIAAIIIALNNILVILVPTIKY 476

  Fly   449 VIGTYTSLKEIVLTF 463
            :.|...:....:|.|
Mouse   477 IFGFIGASSATMLIF 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7888	NP_648425.1	SLC5-6-like_sbd	51..453	CDD:294310	87/483 (18%)
CG7888	NP_648425.1	SdaC	62..456	CDD:223884	85/475 (18%)
Slc38a4	NP_001344987.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..34
Slc38a4	NP_001344987.1	SLC5-6-like_sbd	75..535	CDD:382020	89/493 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849026
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840