DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7888 and slc36a1

DIOPT Version :9

Sequence 1:	NP_648425.1	Gene:	CG7888 / 39232	FlyBaseID:	FBgn0036116	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	XP_021336836.1	Gene:	slc36a1 / 559308	ZFINID:	ZDB-GENE-061117-1	Length:	468	Species:	Danio rerio

Alignment Length:	470	Identity:	172/470 - (36%)
Similarity:	259/470 - (55%)	Gaps:	48/470 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 DHPDKLELAEKGQKNKAVVAKDPDYNPYHHRDVEHP-----TTNS--ETLFHLLKGSLGTGILAM 74
            |.||      ..:::::....:|.::| ..|..|:.     |.:|  :|:.|||||::|||:|.:
Zfish     9 DGPD------FSRRDESPTEDEPIHSP-GSRQTEYERIGGRTGSSVLQTIIHLLKGNIGTGLLGL 66

  Fly    75 PNAFRNSGYITGSIGTIVIGFICTFCIHQLVKAQYELCRRKKMPSMNYPMVAETAMGEGPKCFRV 139
            |.|.||:|.:.|.:..:::|.:...|::.|||..:.|..:...|.::|....|..| |.......
Zfish    67 PLAVRNAGLLVGPLSLLIMGIVAVHCMNLLVKCAHHLSAKLGKPFLSYGDAVEYGM-ENVSWLSR 130

  Fly   140 FAPYIGTVVNTFLLIYQLGTCCVYVVFVASNIKAIVD--------------AVADTSIDVRLCMI 190
            .:.:...|||.||.|.|||.||||.||::.|:|.:|:              ||...|.|.||.|:
Zfish   131 HSIWGRHVVNLFLNITQLGFCCVYFVFLSDNVKQVVETANATTGNCHNNETAVPVPSYDSRLYMV 195

  Fly   191 IILLPLILINWVRNLKYLAPFSTLANAITMVSFGIICYYIFREPVTTEGKDAFGKPSNFPLFFGT 255
            ..|..:||:.::||||||||.|..||.....|..:|.||..............|:.:::||||||
Zfish   196 FFLPFIILLVFIRNLKYLAPLSFAANICMCASLVLIYYYCLTNIPNPINLPLAGRGADYPLFFGT 260

  Fly   256 VLFALEAIGVILPLENEMKTPQKFGGSCGVLNVSMVLIVFLYVGMGLFGYLNYGSAVLGSITLNM 320
            .:||.|.|||:|||||:|:.|:.|   ..||.:.|.::.|||:.:|..||:.:|..:.||||||:
Zfish   261 AIFAFEGIGVVLPLENKMQNPRNF---TKVLYLGMGIVTFLYISLGTIGYIGFGEEIRGSITLNL 322

  Fly   321 PEHEVLSMC-----VKGMLAFAIYITHGLACYVAIDITWNDYVAKRLGAQRNALFWEYAVRTGLV 380
            |      :|     ||.:.:|.||||:.|..||:.:|.....|| |.| .|.||..:.::|..||
Zfish   323 P------LCWLYQIVKLLYSFGIYITYALQFYVSAEILIPPAVA-RCG-PRWALMVDLSIRVALV 379

  Fly   381 LITFLLAVAIPNLELFISLFGALCLSALGLAFPALIQICTHWYNTKGFAKVWLVLSNFVLIIVGI 445
            .:|..||:.||.|:|.|||.|::..|||.|..|.|:||.| ::|..  .|.|:...:.::.::|.
Zfish   380 GLTCALAILIPELDLVISLVGSVSSSALALIIPPLLQIIT-FHNED--MKPWVFAKDILISVLGF 441

  Fly   446 LGLVIGTYTSLKEIV 460
            :|.:.|||||::|||
Zfish   442 VGFIAGTYTSIQEIV 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7888	NP_648425.1	SLC5-6-like_sbd	51..453	CDD:294310	158/427 (37%)
CG7888	NP_648425.1	SdaC	62..456	CDD:223884	157/412 (38%)
slc36a1	XP_021336836.1	SLC5-6-like_sbd	44..453	CDD:320982	161/423 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594522
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	312	1.000	Inparanoid score	I2564
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22950
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X121
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	9.010