DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7888 and slc36a4

DIOPT Version :9

Sequence 1:	NP_648425.1	Gene:	CG7888 / 39232	FlyBaseID:	FBgn0036116	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	XP_002664741.3	Gene:	slc36a4 / 504109	ZFINID:	ZDB-GENE-050309-239	Length:	488	Species:	Danio rerio

Alignment Length:	484	Identity:	152/484 - (31%)
Similarity:	248/484 - (51%)	Gaps:	81/484 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 LAEKGQKNKAVVAKDPDYNPYHHRDVEH---PTTNSETLFHLLKGSLGTGILAMPNAFRNSGYIT 85
            |.||.:..:    ::.|.|.....|.:|   ..|.::||.|||||::|||:|.:|.|.:|:|.:.
Zfish    15 LMEKAEGEE----EEEDENVDGDEDSKHLPQGITFTQTLLHLLKGNIGTGLLGLPLAVKNAGIVL 75

  Fly    86 GSIGTIVIGFICTFCIHQLVKAQYELCRRKKMPSMNYPMVAETAMG-EGPKCFRVFAPYIGTVVN 149
            |.:..:::|.:|..|:|.||...::|..|.|...:.|......||. ...:|.|..|.:...:||
Zfish    76 GPVSLVLMGVVCVHCMHILVNCSHQLSERLKRSPLGYSETVAAAMELSSSQCLRRSAHFGRHLVN 140

  Fly   150 TFLLIYQLGTCCVYVVFVASNIKAIVD-----AVADT----------------SIDVRLCMIIIL 193
            .||::.|||.|.||.||:|.|||.:::     :.|:|                :||:||.|:.:|
Zfish   141 FFLVLTQLGFCSVYFVFLAENIKQVMEGTHMNSTAETVLLSSNSSEASVASSVAIDLRLYMVFLL 205

  Fly   194 LPLILINWVRNLKYLAPFSTLANAITMVSFGIICYYIF-------REPVTTEGKDAFGKPSNFPL 251
            ..:|::.::|:|:.:|..|.:||....:|...|..||.       |.|..:..:       .||.
Zfish   206 PFIIVLTFIRDLRNMAALSAIANLCMAISLIFIFSYILNDLSDPRRLPYASTWR-------KFPF 263

  Fly   252 FFGTVLFALEAIGVILPLENEMKTPQKFGGSCGVLNVSMVLIVFLYVGMGLFGYLNYGSAVLGSI 316
            ||||.:||.|.|||:|||||:|:.|::|..:   ||:.|..|:.|||.:...|||.:...:.|||
Zfish   264 FFGTAIFAFEGIGVVLPLENQMREPKRFPQA---LNIGMGFIIVLYVTLATLGYLRFRDDIKGSI 325

  Fly   317 TLNMPEHEVLSMCVKGMLAFAIYITHGLACYVAIDI-----------TWNDYVAKRLGAQRNALF 370
            |||:|.....:..||.:.:|.::::..:..:|..:|           :|     :|:.
Zfish   326 TLNLPHDSWSNQLVKVLYSFGVFVSFAVQFFVPAEILLPPMCERVRKSW-----RRVA------- 378

  Fly   371 WEYAVRTGLVLITFLLAVAIPNLELFISLFGALCLSALGLAFPALIQICTHWYNTKGFAK----V 431
             :.::|..||.:|.:.||.||.|:|.|||.||:..|||.|.||.|:::.       .|..    .
Zfish   379 -DLSLRALLVCLTCVTAVLIPRLDLVISLVGAVSSSALALVFPPLVELI-------AFPSQPPPP 435

  Fly   432 WLVLSNFVLIIVGILGLVIGTYTSLKEIV 460
            .|:|.:..:..:|.:|.:.|||.:::||:
Zfish   436 MLLLKDISIAALGFIGFLTGTYVTVEEII 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7888	NP_648425.1	SLC5-6-like_sbd	51..453	CDD:294310	142/448 (32%)
CG7888	NP_648425.1	SdaC	62..456	CDD:223884	139/437 (32%)
slc36a4	XP_002664741.3	SLC5-6-like_sbd	42..460	CDD:294310	143/447 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594557
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	312	1.000	Inparanoid score	I2564
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22950
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X121
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	10.010