DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7888 and slc38a2

DIOPT Version :9

Sequence 1:	NP_648425.1	Gene:	CG7888 / 39232	FlyBaseID:	FBgn0036116	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_001011056.1	Gene:	slc38a2 / 496466	XenbaseID:	XB-GENE-6258676	Length:	493	Species:	Xenopus tropicalis

Alignment Length:	512	Identity:	111/512 - (21%)
Similarity:	186/512 - (36%)	Gaps:	131/512 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 DKLELAEKGQKNKAVVAKDPDYNPYHHRDVEH------PTTNSE---------------TLFHLL 63
            |.|..:|...||..:       ..::..|:|:      ||.:.:               ::|:|.
Frog    20 DDLNYSEYQPKNHPI-------KSHYDMDIENVHFLLEPTMSKKKCETEYLPGTTSFGMSVFNLS 77

  Fly    64 KGSLGTGILAMPNAFRNSGYITGSIGTIVIGFICTFCIHQLVKAQYELCRRKKMPSMNYPMVAET 128
            ...:|:|||.:..|..|:|.....|..:.:.....:.||.|:|...|      ..|:.|..:...
Frog    78 NAIVGSGILGLSYAMANTGIALFMILLVFVTVFSLYSIHLLLKTANE------GGSLLYEQLGLK 136

  Fly   129 AMGEGPKCFRVFAPYIGTVVNTFLLIYQLGTCCVYVVFVASNIKAIVDAVADTSID--------- 184
            |.|...|          ...:..:.:..:|....|:..|...:..::.|:.|....
Frog   137 AFGIPGK----------LAASGSVTLQNIGAMSSYLYIVKYELPLVIKALMDIKESNGEWYLNGD 191

  Fly   185 --VRLCMIIILLPLILINWVRNLKYL---APFSTLANAITMVSFGIICYYIFREPVTTEG----- 239
              |.:..:.|:|||.|:   |||.||   :.||.|.....::   ::.|..|..|...|.
Frog   192 YLVIMVSLAIILPLSLL---RNLGYLGYTSGFSPLCMVFFLI---VVIYKKFEIPCPLEAMNMTS 250

  Fly   240 -------------KDAFGKPSNFPLFFGTVLFALEAI-------GVILPLENEMKTPQKFGGS-- 282
                         .|...||..| :|....::|:..:       ..:||:..|:|     |.|
Frog   251 NSSSHDHMAHNETDDEMCKPKYF-VFNSQTVYAVPILTFSFVCHPAVLPIYQELK-----GRSRR 309

  Fly   283 --CGVLNVSMVLIVFLYVGMGLFGYLNYGSAVLGSITLNMPEHEVLSMCVKGMLAFAIYITHGLA 345
              ..|.|||...:..:|:...|||||.:.|.|         |.|:|....|...|..|::...||
Frog   310 RMMNVSNVSFFAMFIMYLLAALFGYLTFYSKV---------EPELLHTYSKVFGAGVIFVVVRLA 365

  Fly   346 CYVAIDITWNDYVAKRLGAQRNALF-------WEYAVRTGLVLITFL-------LAVAIPNLELF 396
            ..:|:.:| ...|...:.:..|.||       |   :|.  :|||||       |.:.:|.:...
Frog   366 VLMAVTLT-VPIVIFPIRSSLNELFCSGKDFAW---IRH--ILITFLILAFTNVLVIFVPTIRDI 424

  Fly   397 ISLFGALCLSALGLAFPALIQI-CTHWYNTKGFAKV--WLVLSNFVLIIVGILGLVI 450
            ....||...:.|....|:...| .....:.|...|:  .|.|...:::::|.:.|:|
Frog   425 FGFIGASAAAMLVFILPSAFYIRLVKKESMKSVQKIGALLFLIGGIIVMIGSMTLII 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7888	NP_648425.1	SLC5-6-like_sbd	51..453	CDD:294310	104/481 (22%)
CG7888	NP_648425.1	SdaC	62..456	CDD:223884	101/449 (22%)
slc38a2	NP_001011056.1	Regulates protein turnover upon amino acid deprivation. /evidence=ECO:0000250	1..92		15/78 (19%)
		SdaC	63..485	CDD:223884	102/462 (22%)
		SLC5-6-like_sbd	65..482	CDD:294310	102/460 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920