DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7888 and slc38a6

DIOPT Version :9

Sequence 1:	NP_648425.1	Gene:	CG7888 / 39232	FlyBaseID:	FBgn0036116	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_001008117.2	Gene:	slc38a6 / 493479	XenbaseID:	XB-GENE-1016511	Length:	448	Species:	Xenopus tropicalis

Alignment Length:	511	Identity:	115/511 - (22%)
Similarity:	199/511 - (38%)	Gaps:	119/511 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 VMTKNGHSNSAYVADHPDKLELAEKGQ-KNKAVVAKDPDYNPYHHRDVEHPTTNSETLFHLLKGS 66
            :.|.:||..||              |: ::..::|..|      .|.....|:....:|:|:...
Frog     8 INTLDGHQVSA--------------GRDESTPLLANSP------QRRSSGGTSFGFAVFNLMNAI 52

  Fly    67 LGTGILAMPNAFRNSGYITGSIGTIVIGFICTFCIHQLVKAQYELCRRKKMPSMNYPMVAETAMG 131
            :|:|||.:..|...:|.:..|...:::..:..:.||.|::    :|....:.|  |..:...|.|
Frog    53 MGSGILGLSYAMAKTGILGFSALLLIVALLAAYSIHLLLR----MCLLTAVTS--YEDLGLYAFG 111

  Fly   132 EGPKCFRVFAPYIGTVVNTFLLIYQLGTCCVYVVFVASNIKAIVDAVADTS------IDVRLCMI 190
            ...|          .:|...:||..:|....|:..:.|.:.|.:.:....:      :|.|..:|
Frog   112 RSGK----------VLVACTILIQNVGAMSSYLFIIKSELPAAIASFLPGAQGEPWYLDGRTLLI 166

  Fly   191 I----ILLPLILINWVRNLKYLAPFS-----TLANAITMVSFGIIC--------YYIFREPVTTE 238
            |    |:|||.|:..:..|.|.:..|     ..|..|.:..:.|.|        ....:.|..:|
Frog   167 ITSVCIVLPLALLPKIGFLGYTSSLSFFFMVYFAVVIVIKKWNIPCPLPPLNHTVTFLQAPNISE 231

  Fly   239 GKDA---FGKPSNFPLFFGTVLFALEAIGVILPLENEMKTPQKFGGSCGVLNVSMVLIVFLYVGM 300
            .|..   |.|.|.|.|  .|:.|:......:||:..|:|:|.| .....|.||.:.|...:|...
Frog   232 CKPKLFDFSKESAFAL--PTMAFSFLCHTSVLPIYCELKSPSK-SKMQNVANVGIALSFLIYYIS 293

  Fly   301 GLFGYL----NYGSAVLGSITLNMPEHEVLSMCVKGMLAFAIYITHGLACYVAIDITWNDYVAKR 361
            .|||||    |..|.:|...:..:|: :||.:.|:..:..|:.:|..|..:.|
Frog   294 ALFGYLTFYDNVKSELLQGYSKYLPK-DVLIITVRLCILLAVLLTVPLIHFPA------------ 345

  Fly   362 LGAQRNAL----FWEYA---VRTGLV-----LITFLLAVAIPNLELFISLFGALCLSALGLAFPA 414
                |.|:    |..|.   :|..||     :|..|||:.:|::.....:.|:...:.|...||.
Frog   346 ----RKAVMMMFFSRYPFSYIRHILVTLVLNIIIVLLAIYVPDMRSVFGVVGSTTSTCLLFVFPG 406

  Fly   415 LIQI------CTHWYNTKGFAKVWLVLSNFVLIIVGILGLVIGTYTSLKEIVLTFS 464
            |..:      |:   :.:.|....|:          :||:.||. .||..|::..:
Frog   407 LFYVKLGREDCS---SPQKFGACGLL----------VLGICIGA-CSLTLIIMNLA 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7888	NP_648425.1	SLC5-6-like_sbd	51..453	CDD:294310	103/449 (23%)
CG7888	NP_648425.1	SdaC	62..456	CDD:223884	101/441 (23%)
slc38a6	NP_001008117.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..36		9/47 (19%)
slc38a6	NP_001008117.2	SLC5-6-like_sbd	37..412	CDD:382020	96/410 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920