DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7888 and slc38a7

DIOPT Version :9

Sequence 1:	NP_648425.1	Gene:	CG7888 / 39232	FlyBaseID:	FBgn0036116	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_001003648.1	Gene:	slc38a7 / 445254	ZFINID:	ZDB-GENE-040801-266	Length:	465	Species:	Danio rerio

Alignment Length:	485	Identity:	102/485 - (21%)
Similarity:	195/485 - (40%)	Gaps:	72/485 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 PDKLELAEKGQ-------KNKAVVAKDPDYN----PYHHRDVEHPTTNSETLFHLLKGSLGTGIL 72
            ||:...:|.|.       ..:|.:.:.|..:    |....|....|::...:|.::..:||.|:|
Zfish     4 PDRAINSEAGDWGYSEDAGERAWLLQSPSVDSVQPPSQSDDSRGGTSSLGAVFIVVNAALGAGLL 68

  Fly    73 AMPNAFRNSGYITGSIGTIVIGFICTFCIHQLVKAQYELCRRKKMPSMNYPMVAETAMGEGPKCF 137
            ..|.||..:|.||.  |..:...:..|.|..||...|  |.:....| .|..|.....|:.
Zfish    69 NFPAAFNMAGGITA--GVTLQMCMMAFIITGLVILAY--CSQVSNES-TYQEVVRAVCGKA---- 124

  Fly   138 RVFAPYIGTVVNTFLLIYQLGTCCVYVVFVASNIKAIVDAV-------------ADTSIDVRLCM 189
                  :|.:....:.:|..|||..:::.:...:..::.|:             .|....:.|..
Zfish   125 ------LGVICELAIAVYTFGTCIAFLIIIGDQLDKLIGAINNESEKEISLHWYTDRKFTITLTS 183

  Fly   190 IIILLPLILINWVRNLKYLAPFSTLAN-AITMVSFGIICYYIFREPVTTEGKDAFGKPSNFPLFF 253
            ::|:|||.:...:...||.:..|.:.. .:|::   :|..||:.....:.|.... :|:::...|
Zfish   184 VLIILPLSIPKEIGFQKYASTLSVIGTWYVTII---VIVKYIWPSKDVSPGIIPV-RPASWTDVF 244

  Fly   254 G---TVLFALEAIGVILPLENEMKTPQKFGGSCGVLNVSMVLIVFLYVGMGLFGYLNYGSAVLGS 315
            .   |:.|..:.....:|:.|.||.|: .....||:.:||::.:|:|.|.|:.|:|::||:|...
Zfish   245 NAMPTICFGFQCHVSSVPVFNSMKKPE-IRPWWGVVTISMIICLFVYTGTGVCGFLSFGSSVSQD 308

  Fly   316 ITLNMPEHEVLSMCVKGMLAFAIYITHGLACY---VAIDITW---------NDYVAKRLGAQRNA 368
            :.::.|..:|.....:..:...:..::.:..:   ..::..|         .|...:|.......
Zfish   309 VLMSYPSDDVAVAIARAFIIICVVTSYPILHFCGRAVLEGLWLRFKGEEVETDVAKERRRRILQT 373

  Fly   369 LFWEYAVRTGLVLITFLLAVAIPNLELFISLFGALCLSALGLAFPALIQICTHWYNTKGFAKVWL 433
            |.|        ..:|.:||:.||::...|||.|.|....: ..||.|..|..........:..|.
Zfish   374 LVW--------FCLTLILALFIPDIGRVISLIGGLAACFI-FVFPGLCLIQAKLSEHDVRSNSWN 429

  Fly   434 VLSNFVLIIVGILGLVIGTYTS---LKEIV 460
            .:..:.:|:|.|...:.|..|:   .|:|:
Zfish   430 AMVAYGVIMVTIGAFIFGQTTTNAIYKDII 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7888	NP_648425.1	SLC5-6-like_sbd	51..453	CDD:294310	91/430 (21%)
CG7888	NP_648425.1	SdaC	62..456	CDD:223884	90/425 (21%)
slc38a7	NP_001003648.1	SLC5-6-like_sbd	47..454	CDD:294310	92/435 (21%)
slc38a7	NP_001003648.1	SdaC	47..446	CDD:223884	90/427 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594571
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.750