DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7888 and CG30394

DIOPT Version :9

Sequence 1:	NP_648425.1	Gene:	CG7888 / 39232	FlyBaseID:	FBgn0036116	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_611578.1	Gene:	CG30394 / 37437	FlyBaseID:	FBgn0050394	Length:	831	Species:	Drosophila melanogaster

Alignment Length:	463	Identity:	98/463 - (21%)
Similarity:	172/463 - (37%)	Gaps:	129/463 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 NSETLFHLLKGSLGTGILAMPNAFRNSGYITGSIGTIVIGFICTFCIHQLVKAQYELCRRKKMPS 119
            :|..:..|....:|.||||||..|:..|.:...:..::...|...|.|.|:|... |.||:
  Fly     4 HSAHVMTLANSIIGVGILAMPFCFQKCGILLSIVLLVLSNGITRVCCHYLIKTSL-LTRRR---- 63

  Fly   120 MNYPMVAETAMGEGPKCFRVFAPYIGTVVNTFLLIYQLGTCCVYVVFVASNIKAIVDAVADTSID 184
             ::.|:...|.|...|          .:|...::.|.:|||..|.|.|......|:..:  .::|
  Fly    64 -SFEMLGLHAFGTSGK----------LLVELCIIGYLIGTCITYFVVVGDLGPQIIAKI--FALD 115

  Fly   185 V-------RLCMIIILLPLIL-INWVRNLKYLAPFSTLANAITMVSFGIICYYIFR-----EPVT 236
            |       .|.|:::.:..|: :..:||:..|       :|:...|.|.....|.:     :|..
  Fly   116 VADHLHLRSLVMVVVTVVCIVPLGMLRNVDSL-------SAVCTASIGFYVCLILKIVLEAQPHI 173

  Fly   237 TEG----KDAFGKPSN----FPLFFGTVLFALEAIGVILPLENEMKTPQKFGGSCGVLNVSMVLI 293
            |..    |..:.:|:.    .|:|...:...::...|...:.|     |......|::..:..:.
  Fly   174 TANDWTEKVLYWEPAGVLQCLPIFSMALSCQMQLFEVFESINN-----QSLDKLNGIVRNATWIC 233

  Fly   294 VFLYVGMGLFGYL-----------------NYGSAVLG-----SITLNMPEHEVLSMC------- 329
            .|:|:.:|.|||:                 ::||.::.     ||..:.|  .|:..|
  Fly   234 TFVYISVGFFGYVAFCTHTFSGNILVNLSTSFGSDIIKIGFVLSIAFSFP--LVIFPCRASLYSL 296

  Fly   330 --VKGMLAFAIYITHGLACYVAIDITWNDYVAKRLGAQRNALFWEYAVRTGLVLITFLLAVAIPN 392
              .||....:.||......::.|.|                           |:.:..:|:.||:
  Fly   297 LYRKGHTESSSYIPEQRFRFITIFI---------------------------VVFSLCVALVIPS 334

  Fly   393 LELFISLFGALCLSALGLAFPALIQICTHWYNTKGFAKV------WLVLSNFVLIIVGILGLVIG 451
            :||.|.|.|:....|:.:.|||           ..|.|:      ...|:.|| .:.|.|.:::|
  Fly   335 VELIIGLVGSTIGVAICIMFPA-----------SSFRKIIKKESMERTLAQFV-FVSGFLLMILG 387

  Fly   452 TYTSLKEI 459
            ||.:|..|
  Fly   388 TYANLSAI 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7888	NP_648425.1	SLC5-6-like_sbd	51..453	CDD:294310	94/455 (21%)
CG7888	NP_648425.1	SdaC	62..456	CDD:223884	95/451 (21%)
CG30394	NP_611578.1	SdaC	8..392	CDD:223884	95/454 (21%)
		SLC5-6-like_sbd	8..390	CDD:294310	94/452 (21%)
		DUF4775	<394..652	CDD:292620	1/2 (50%)
		YukC	<561..660	CDD:295067
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468294
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22950
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840