DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7888 and polyph

DIOPT Version :9

Sequence 1:	NP_648425.1	Gene:	CG7888 / 39232	FlyBaseID:	FBgn0036116	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_610631.1	Gene:	polyph / 36161	FlyBaseID:	FBgn0033572	Length:	460	Species:	Drosophila melanogaster

Alignment Length:	459	Identity:	150/459 - (32%)
Similarity:	243/459 - (52%)	Gaps:	28/459 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 EKGQKNKAVVAKDPD-----------------YNPYHHRDVEHPTTNSETLFHLLKGSLGTGILA 73
            |...:::|....|||                 ||||..|.||.|.||.:....|||..:||||||
  Fly     2 EPKSQDQAPNRDDPDLQTEPLTIAQSITSFYMYNPYEKRSVEVPLTNCDAFISLLKCVIGTGILA 66

  Fly    74 MPNAFRNSGYITGSIGTIVIGFICTFCIHQLVKAQYELCRRKKMPSMNYPMVAETAMGEGPKCFR 138
            ||.|||.||::.|::.:|::..:.|:.||.|:....|.|||:::|.::.|.....|..||||...
  Fly    67 MPLAFRCSGFVMGTVMSILLMILLTYSIHLLIADMTECCRRRRVPQVSMPEAVRIAYEEGPKWIN 131

  Fly   139 VFAPYIGTVVNTFLLIYQLGTCCVYVVFVASNIKAIVDAVADTSIDVRLCMI--IILLPLILINW 201
            .|....|.:....|:..|...|.||:|||:.|.|.|.|...:...:....::  ::||||.:|
  Fly   132 CFGRAAGFMTTCVLVFGQFLLCTVYLVFVSKNFKEIGDHYIERYNERYYVLVACLLLLPLFMI-- 194

  Fly   202 VRNLKYLAPFSTLANAITMVSFGIICYYIFREPVTTEGKDAFGKPSNFPLFFGTVLFALEAIGVI 266
             |.||||.|.:.::|.:....|.:|.||:|........::....|..:..|.....|:|.|:|.:
  Fly   195 -RRLKYLVPLNLISNFLLYAGFALIMYYLFNGLPNINDREMVTPPVEWIEFIAIAAFSLTAVGSM 258

  Fly   267 LPLENEMKTPQKFGGSCGVLNVSMVLIVFLYVGMGLFGYLNYGSAVLGSITLNMPEHEVLSMCVK 331
            |.:|..|..||.:.|..||||::::.|:...:..|:.||..:|..|..|||||:|:.|:||..:|
  Fly   259 LVVEAHMAHPQSYLGLFGVLNLAVLFILLSNMFFGIIGYWRFGDNVHASITLNIPQDEILSQFIK 323

  Fly   332 GMLAFAIYITHGLACYVAIDITWNDYV-AKRLGAQRNALFWEYAVRTGLVLITFLLAVAIPNLEL 395
            ..:|..|::::.|..:|.|.:.::||. ::..|..|..:  ||.||...:.:|..:|:.:|||..
  Fly   324 VFIASGIFLSYPLNGFVVITVMFSDYENSEPRGRYRTLI--EYVVRLLFLFLTGAVAIGVPNLAA 386

  Fly   396 FISLFGALCLSALGLAFPALIQICTHWYNTKGFAK-VWLVLSNFVLIIVGILGLVIGTYTSLKEI 459
            ...|.||..||.|.|..||||.:..: ||. |:.: :|.::.:.:||::|::..::|...:|.::
  Fly   387 LTELEGAFSLSNLNLLCPALIDVFLN-YNV-GYGRLMWKLIRDILLILIGLIFGIVGCTVALMQL 449

  Fly   460 VLTF 463
            :..|
  Fly   450 IRDF 453

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7888	NP_648425.1	SLC5-6-like_sbd	51..453	CDD:294310	136/405 (34%)
CG7888	NP_648425.1	SdaC	62..456	CDD:223884	133/397 (34%)
polyph	NP_610631.1	SLC5-6-like_sbd	50..407	CDD:320982	123/361 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466551
Domainoid	1	1.000	157	1.000	Domainoid score	I1306
eggNOG	1	0.900	-	-		E1_COG0814
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1622
Isobase	1	0.950	-	0	Normalized mean entropy	S4217
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	1	1.000	-	-		mtm1178
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22950
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X121
	11	10.850