DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7888 and CG16700

DIOPT Version :9

Sequence 1:	NP_648425.1	Gene:	CG7888 / 39232	FlyBaseID:	FBgn0036116	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_573191.1	Gene:	CG16700 / 32694	FlyBaseID:	FBgn0030816	Length:	468	Species:	Drosophila melanogaster

Alignment Length:	477	Identity:	163/477 - (34%)
Similarity:	262/477 - (54%)	Gaps:	42/477 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 ADHPDKL-----------ELAEKGQKNK-------AVVAKDPDYNPYHHRDVEHPTTNSETLFHL 62
            |:.|::|           |.||.|...:       |.|.|:.|::..:|    .||:..||:.||
  Fly     3 AEAPNQLEKNQTATVPRQETAEGGSTGETAVGGAAAKVTKEQDHDAEYH----PPTSYLETIVHL 63

  Fly    63 LKGSLGTGILAMPNAFRNSGYITGSIGTIVIGFICTFCIHQLVKAQYELCRRKKMPSM------- 120
            .||::|.|:.||.:||:|.|.:...:.|:||..:...|.|.||...      |||..:
  Fly    64 FKGNIGPGLFAMGDAFKNGGLLVAPLLTVVIAVVSIHCQHVLVTCS------KKMRDLKGDSVCA 122

  Fly   121 NYPMVAETAMGEGPKCFRVFAPYIGTVVNTFLLIYQLGTCCVYVVFVASNIKAIVDAVADTSIDV 185
            :|....|.....||...|.::..:|.:|:.|:.:.|||.||:|.||:::|:|.|:.|. |..::|
  Fly   123 DYAQTVEQCFENGPSKLRGWSRTMGRLVDIFICVTQLGFCCIYFVFISTNLKQILQAY-DIDMNV 186

  Fly   186 RLCMIIILLPLILINWVRNLKYLAPFSTLANAITMVSFGIICYYIFREPV-TTEGKDAFGKPSNF 249
            .|.|::..:|::|.:.:.|||:|.|.|..||...::...|..||..::.: ..|.:..:...|..
  Fly   187 HLVMLLAFVPVLLSSLITNLKWLTPVSMFANVCMILGLAITLYYALKDGLPEVEERALWTNGSQL 251

  Fly   250 PLFFGTVLFALEAIGVILPLENEMKTPQKFGGSCGVLNVSMVLIVFLYVGMGLFGYLNYGSAVLG 314
            .|||||.:||.|.|.:::||:|.|:.|.:|....|||||.|.|:..:::..|..||:.:|..|.|
  Fly   252 ALFFGTAIFAFEGIALVMPLKNAMRKPHQFERPLGVLNVGMFLVSVMFMFAGSVGYMKWGEQVGG 316

  Fly   315 SITLNMPEHEVLSMCVKGMLAFAIYITHGLACYVAIDITWNDYVAKRL-GAQRNALFWEYAVRTG 378
            |:|||:.: .:|:..||.|::..:.:.:.|..:|||.|.|.:  ||:: |.:..:|..|...||.
  Fly   317 SLTLNLGD-TILAQAVKLMVSAGVLLGYPLQFFVAIQIMWPN--AKQMCGIEGRSLLGELGFRTF 378

  Fly   379 LVLITFLLAVAIPNLELFISLFGALCLSALGLAFPALIQICTHWYNTKGFAKVWLVLSNFVLIIV 443
            :||:|..:|..:|.|.|||||.||||.:||.|.||.:|::.:.....|| ..:|:.:.|.|::::
  Fly   379 MVLVTLAIAEMVPALGLFISLIGALCSTALALVFPPVIELISRSELNKG-PGIWICVKNLVILVL 442

  Fly   444 GILGLVIGTYTSLKEIVLTFSE 465
            .:||...|:|.|||:||..|.|
  Fly   443 ALLGFFTGSYESLKQIVKHFGE 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7888	NP_648425.1	SLC5-6-like_sbd	51..453	CDD:294310	143/410 (35%)
CG7888	NP_648425.1	SdaC	62..456	CDD:223884	139/402 (35%)
CG16700	NP_573191.1	SLC5-6-like_sbd	53..452	CDD:294310	143/409 (35%)
CG16700	NP_573191.1	SdaC	57..452	CDD:223884	141/405 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45468307
Domainoid	1	1.000	157	1.000	Domainoid score	I1306
eggNOG	1	0.900	-	-		E1_COG0814
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1622
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	1	1.000	-	-		mtm1178
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22950
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X121
	10	9.900