DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7888 and Slc38a2

DIOPT Version :9

Sequence 1:	NP_648425.1	Gene:	CG7888 / 39232	FlyBaseID:	FBgn0036116	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	XP_006242344.1	Gene:	Slc38a2 / 29642	RGDID:	69420	Length:	535	Species:	Rattus norvegicus

Alignment Length:	572	Identity:	108/572 - (18%)
Similarity:	199/572 - (34%)	Gaps:	192/572 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 LELAEKGQKNKAVVAKDPDYNPY-------------------HHRDVE----------------- 50
            ::..|.|:.|   ::.|.|.:.|                   |:.||:
  Rat     1 MKKTEMGRFN---ISPDEDSSSYSSNGDFNYSYPTKQAALKSHYVDVDPENQNFLLESNLGKKKY 62

  Fly    51 ----HPTTNS--ETLFHLLKGSLGTGILAMPNAFRNSGYITGSIGTIVIGFICTF---CIHQLVK 106
                ||.|.|  .::|:|....:|:|||.:..|..|:|.   ::..|::.|:..|   .:|.|:|
  Rat    63 ETDFHPGTTSFGMSVFNLSNAIVGSGILGLSYAMANTGI---ALFIILLTFVSIFSLYSVHLLLK 124

  Fly   107 AQYELCRRKKMPSMNYPMVAETAMGEGPKCFRVFAPYIGTVVNTFLLIYQLGTCCVYVVFVASNI 171
            ...|      ..|:.|..:...|.|...|          ...:..:.:..:|....|:..|...:
  Rat   125 TANE------GGSLLYEQLGHKAYGLAGK----------LAASGSITMQNIGAMSSYLFIVKYEL 173

  Fly   172 KAIVDA---VADTS--------IDVRLCMIIILLPLILINWVRNLKYLAPFSTLANAITMVSFGI 225
            ..::.|   :.||:        ..|.|...:::|||.|:   |||.||...|.| :.:.|:.|.|
  Rat   174 PLVIKALMNIEDTNGLWYLNGDYLVLLVSFVLILPLSLL---RNLGYLGYTSGL-SLLCMIFFLI 234

  Fly   226 I-----------------------------CYYI---FREPVTTE-----GKDAFG--------- 244
            :                             |..|   |:.|...|     .:...|
  Rat   235 VVGVVVFVCRKCILKALSGHPALLTSAIFCCQVICKKFQIPCPVEVALMANETVNGTFTQVALAA 299

  Fly   245 -----------KPSNFPLFFGTVLFALEAI-------GVILPLENEMKTPQKFGGSCGVLNVSMV 291
                       :|..| :|....::|:..:       ..:||:..|:|:..: .....|..:|..
  Rat   300 LASNSTAADTCRPRYF-IFNSQTVYAVPILTFSFVCHPAVLPIYEELKSRSR-RRMMNVSKISFF 362

  Fly   292 LIVFLYVGMGLFGYLNY-----------GSAVLGSITLNMPEHEVLSMCVKGMLAFAIYITHGLA 345
            .:..:|:...|||||.:           .||::|:        ::|.:.|:            ||
  Rat   363 AMFLMYLLAALFGYLTFYEHVESELLHTYSAIVGT--------DILLLVVR------------LA 407

  Fly   346 CYVAIDIT-------WNDYVAKRLGAQRNALFWEYAVRTGLVL-ITFLLAVAIPNLELFISLFGA 402
            ..||:.:|       ....|...|...:...::.::|.|..:| .|.||.:.:|.:.......||
  Rat   408 VLVAVTLTVPVVIFPIRSSVTHLLCPTKEFSWFRHSVITVTILAFTNLLVIFVPTIRDIFGFIGA 472

  Fly   403 LCLSALGLAFPALIQI----CTHWYNTKGFAKVWLVLSNFVLIIVGILGLVI 450
            ...:.|....|:...|    .....:.:....:..:||. |::::|.:||::
  Rat   473 SAAAMLIFILPSAFYIKLVKKEPMRSVQKIGALCFLLSG-VVVMIGSMGLIV 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7888	NP_648425.1	SLC5-6-like_sbd	51..453	CDD:294310	99/503 (20%)
CG7888	NP_648425.1	SdaC	62..456	CDD:223884	94/490 (19%)
Slc38a2	XP_006242344.1	SdaC	64..516	CDD:223884	96/497 (19%)
Slc38a2	XP_006242344.1	SLC5-6-like_sbd	69..518	CDD:294310	94/494 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352639
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840