DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7888 and Slc38a9

DIOPT Version :9

Sequence 1:	NP_648425.1	Gene:	CG7888 / 39232	FlyBaseID:	FBgn0036116	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_848861.1	Gene:	Slc38a9 / 268706	MGIID:	1918839	Length:	560	Species:	Mus musculus

Alignment Length:	518	Identity:	100/518 - (19%)
Similarity:	190/518 - (36%)	Gaps:	139/518 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 NKAVVAKD-----PD----YNPY-------HHRDVEHPTTNSETLFHLLKGSLGTGILAMPNAFR 79
            :||::|.|     |:    |:|.       .:.:.....|:..|:|.:....:||.||::|...:
Mouse    78 DKALIAPDHVVPAPEECYVYSPLGSAYKLKSYTEGYGKNTSLVTIFMIWNTMMGTSILSIPWGIK 142

  Fly    80 NSGYITGSIGTIVIGFICTFCIHQLVKAQYELCRRKKMPSMNYPMVAETAMGEGPK-CFRVFAPY 143
            .:|:.||....:::|.:..:|.:::||::..:            ..::|:..|.|. |...|..:
Mouse   143 QAGFTTGMCVIVLMGLLTLYCCYRVVKSRSTI------------STSDTSTWEYPDVCKHYFGSF 195

  Fly   144 IGTVVNTFLLIYQLGTCCVYVV-----------FVASNIKAIVDAVA------------------ 179
            .......|.|:..:|...||.|           |:.:.|..|.|...
Mouse   196 GQWSSLLFSLVSLIGAMIVYWVLMSNFLFNTGKFIFNFIHHINDTDTVLSTNNSNPVICPNAGSG 260

  Fly   180 ------------------------DTSIDVRLCMIIILLPLILINWVRNLK---YLAPFSTLAN- 216
                                    |.|..|...:|.:||||:      |.|   :.:.|:.|..
Mouse   261 GRPDNSSMIFYNNNTEVQLFEKWWDKSRTVPFYLIGLLLPLL------NFKSPSFFSKFNILGTV 319

  Fly   217 -------AITMVSFGIICYYIFREPVTTEGKDAFGKP---SNFPLFFGTVLFALEAIGVILPL-- 269
                   .:|:.:..:..:..|...|.||    |..|   :.||...|.:..|......|:.|
Mouse   320 SVLYLIFVVTLKAVRLGFHLEFHWFVPTE----FFVPEIRAQFPQLMGVLTLAFFIHNCIITLLK 380

  Fly   270 -----ENEMKTPQKFGGSCGVLNVSMVLIVFLYVGMGLFGYLNYGSAVLGSITL------NMPEH 323
                 ||.::.          |.::.:|:...|:.:|:..:.::.|..|....:      |.|..
Mouse   381 NNKNQENNVRD----------LCIAYMLVTLTYLYIGILVFASFPSPPLPKDCIEQNFLDNFPSS 435

  Fly   324 EVLSMCVKGMLAFAIYITHGLACYVA-IDITWNDYVAKRLGAQRNALFWEYAVRTGLVLITFLLA 387
            ::||...:..|.|.:...:.|..|:| :.:..:.:     |....::|....:...:|.....:|
Mouse   436 DILSFIARIFLLFQMMTVYPLLGYLARVQLLGHIF-----GDIYPSIFHVLILNLVIVGAGVTMA 495

  Fly   388 VAIPNLELFISLFGALCLSALGLAFPALIQICT-HWYNTKGFAKVWLVLSNFVLIIVGILGLV 449
            ...||:...|...||.|..|....:|:||.|.: |......:.|   ::.:.::||:|:..|:
Mouse   496 CFYPNIGGIIRYSGAACGLAFVFIYPSLIYIISLHQEERLTWPK---LVFHVIIIILGLANLI 555

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7888	NP_648425.1	SLC5-6-like_sbd	51..453	CDD:294310	93/482 (19%)
CG7888	NP_648425.1	SdaC	62..456	CDD:223884	90/471 (19%)
Slc38a9	NP_848861.1	SLC5-6-like_sbd	114..556	CDD:382020	93/482 (19%)
Slc38a9	NP_848861.1	Important for arginine binding and amino acid transport. /evidence=ECO:0000250\|UniProtKB:Q08BA4	128..133		1/4 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849041
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830