DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG7888 and Slc38a8

DIOPT Version :9

Sequence 1:NP_648425.1 Gene:CG7888 / 39232 FlyBaseID:FBgn0036116 Length:465 Species:Drosophila melanogaster
Sequence 2:NP_001009950.1 Gene:Slc38a8 / 234788 MGIID:2685433 Length:432 Species:Mus musculus


Alignment Length:459 Identity:95/459 - (20%)
Similarity:170/459 - (37%) Gaps:117/459 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    51 HPTTNS-ETLFHLLKGSLGTGILAMPNAFRNSGYITGSIGTIVIGFI-CTFCIHQLVKAQY---- 109
            |||.:| ..:|.|||.:||.|:|..|.||..:|   |.:.|.::..: ..|.|..||...|    
Mouse    21 HPTLSSLGAVFILLKSALGAGLLNFPWAFYKAG---GMLPTFLVALVSLVFLISGLVILGYAASV 82

  Fly   110 -----------ELCRRKKMPSMNYPMVAETAMGEGPKCFRVFAPYIGTVVNTFLLIYQLGTCCVY 163
                       |||                            .|.:|.:.....|...|.....:
Mouse    83 SGQTTYQGVVRELC----------------------------GPAMGKLCEICFLTNLLMISVAF 119

  Fly   164 VVFVASNIKAIVDAV---------ADTSIDVRLCMIIILLPLILINWVRNLKYLAPFSTLANAIT 219
            :..:...::.:.|::         |..:..:.|..::::.||..:..:...||.:...||| |..
Mouse   120 LRVIGDQLEKLCDSLLPDAPQPWYAAQNFTLPLISMLVIFPLSALREIALQKYTSILGTLA-ACY 183

  Fly   220 MVSFGIICYYIF-----REPVTTEGKDAFGKPSNFPLFFG---TVLFALE----AIGVILPLENE 272
            :.....:.||::     |:|      .....||.:...|.   |:.|..:    |:.:...:.| 
Mouse   184 LALVITVQYYLWPQGLIRQP------GPLLSPSPWTSVFSVFPTICFGFQCHEAAVSIYCSMWN- 241

  Fly   273 MKTPQKFGGSCGVLNVSMVLIVFLYVGMGLFGYLNYGSAVLGSITLNMPEHEVLSMCVKGMLAFA 337
                |.......|..:|::....:|...|::|:|.:|..|...|.::.|.::...:..:.:.|.:
Mouse   242 ----QSLSHWTLVSVLSLLACCLVYTLTGVYGFLTFGPEVSADILMSYPGNDTAIIVARVLFAVS 302

  Fly   338 IYITHGLACYVAIDITWNDYVAKRLGAQRNALF-------WEYAVRTGL----VLITFLLAVAIP 391
            |...:.:..::...: ..|:..|...|.|....       |   ||..|    |::|..:|:.:|
Mouse   303 IVTVYPIVLFLGRSV-MQDFWKKSYWATRGPPVLADPSGPW---VRLPLTFLWVVVTLTMALFLP 363

  Fly   392 NLELFISLFGALCLSALGLAFPALIQICTHWYNT-------KGFAKVWLVLSNFVLIIVGILGLV 449
            :|...||:.|.:. |.....||.|..||.  .:|       |...:.|           |||.::
Mouse   364 DLSEIISIIGGVS-SFFIFIFPGLCLICA--VDTEPMGPRVKCCLEAW-----------GILSVL 414

  Fly   450 IGTY 453
            :||:
Mouse   415 VGTF 418

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7888NP_648425.1 SLC5-6-like_sbd 51..453 CDD:294310 94/457 (21%)
SdaC 62..456 CDD:223884 90/447 (20%)
Slc38a8NP_001009950.1 SdaC 23..429 CDD:223884 93/457 (20%)
SLC5-6-like_sbd 23..421 CDD:294310 93/457 (20%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167848945
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0814
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG54358
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
43.750

Return to query results.
Submit another query.