DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7888 and Slc36a3

DIOPT Version :9

Sequence 1:	NP_648425.1	Gene:	CG7888 / 39232	FlyBaseID:	FBgn0036116	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_758462.2	Gene:	Slc36a3 / 215332	MGIID:	2665001	Length:	477	Species:	Mus musculus

Alignment Length:	471	Identity:	152/471 - (32%)
Similarity:	240/471 - (50%)	Gaps:	69/471 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 AEKGQKN-KAVVAKDPDYNPYHHRDVEHPTTNSETLFHLLKGSLGTGILAMPNAFRNSGYITGSI 88
            :.||..| ::..:..|...|....|.   ....:...||||.::|||.|.:|.|.:|:|.:.|.:
Mouse    24 SSKGSSNSRSSSSTSPKKGPRREADA---LMFIQIFIHLLKSNIGTGFLGLPLAVKNAGLLVGPV 85

  Fly    89 GTIVIGFICTFCIHQLVKAQYELCRRKKMPSMNYPMVAETAMGEGPKCFRVFAPYIGT------- 146
            ..:.||.:...|:..|:.....|.:|.:...:||   .||.|.....|   .:|::.|
Mouse    86 SLLAIGALTVHCMDILLNCACHLTQRLQRSFVNY---EETTMYSLETC---PSPWLRTHSVWGRY 144

  Fly   147 VVNTFLLIYQLGTCCVYVVFVASNIKAIVDAVADTS--------------IDVRLCMIIILLPLI 197
            ||:..|::.|||.|.||.:|:|.|::.|::....||              :|.|..|:.||..||
Mouse   145 VVSFLLIVTQLGFCSVYFMFLADNLQQIMEEAHFTSNVCQPRQSLVMTSILDTRFYMLTILPFLI 209

  Fly   198 LINWVRNLKYLAPFSTLANAITMVSFGIICYYIFREPVTTEGKDAFGKPSNFP---------LFF 253
            |:..::|.:.|:.|||||...|:.|..:|..|:.:.|          ..||.|         |||
Mouse   210 LLVLIQNPQVLSIFSTLATITTLSSLALIFEYLIQTP----------HHSNLPLVANWKTFLLFF 264

  Fly   254 GTVLFALEAIGVILPLENEMKTPQKFGGSCGVLNVSMVLIVFLYVGMGLFGYLNYGSAVLGSITL 318
            ||.:|..|.:|::|||:::||:||:|.   .||.:.|..::|||:.:|..||:.:|:....||||
Mouse   265 GTAIFTFEGVGMVLPLKSQMKSPQQFP---AVLYLGMSFVIFLYICLGTLGYMKFGTDTQASITL 326

  Fly   319 NMPEHEVLSMC-----VKGMLAFAIYITHGLACYVAIDITWNDYVAKRLGAQRNALFWEYAVRTG 378
            |:|      :|     ||.|.:..|:.|:.|..:|..:|. ..||..|: ::..|||.:..|||.
Mouse   327 NLP------ICWLYQSVKLMYSVGIFFTYALQFHVPAEII-VPYVVSRV-SENWALFVDLTVRTA 383

  Fly   379 LVLITFLLAVAIPNLELFISLFGALCLSALGLAFPALIQICTHWYNTKGFAKVWLVLSNFVLIIV 443
            ||.:|...||.||.|:|.|||.|::..|||.:..|.|::|.|.:......|   .::.:.::.|:
Mouse   384 LVCLTCFSAVLIPRLDLVISLVGSVSSSALAIIIPPLLEIATFYSENISCA---TIVKDIMISIL 445

  Fly   444 GILGLVIGTYTSLKEI 459
            |:||.|:|||.:|.|:
Mouse   446 GLLGCVLGTYQALYEM 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7888	NP_648425.1	SLC5-6-like_sbd	51..453	CDD:294310	142/436 (33%)
CG7888	NP_648425.1	SdaC	62..456	CDD:223884	143/428 (33%)
Slc36a3	NP_758462.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	19..43		4/18 (22%)
Slc36a3	NP_758462.2	SLC5-6-like_sbd	52..458	CDD:382020	144/435 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849014
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	1	1.000	-	-		mtm8749
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22950
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X121
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.860