Protein Alignment CG7888 and SLC36A1

DIOPT Version :10

• Sequence 1: NP_648425.1
• Gene: CG7888 / 39232
• FlyBaseID: FBgn0036116
• Length: 465
• Species: Drosophila melanogaster
• Sequence 2: XP_047272876.1
• Gene: SLC36A1 / 206358
• HGNCID: 18761
• Length: 507
• Species: Homo sapiens
• Alignment Length: 473
• Identity: 163/473 - (34%)
• Similarity: 256/473 - (54%)
• Gaps: 68/473 - (14%)

  Fly    37 KDPDYNPYHHRDV---EHP---------------------TTNSETLFHLLKGSLGTGILAMPNA 77
            ::.||:.|...||   |.|                     ||..:||.|||||::|||:|.:|.|
Human    38 RNEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGNIGTGLLGLPLA 102

  Fly    78 FRNSGYITGSIGTIVIGFICTFCIHQLVKAQYELCRRKKMPSMNYPMVAETAMG--EGPKC--FR 138
            .:|:|.:.|.|..::||.:...|:..|||..:..|||.....::|   .:|.|.  |...|  .|
Human   103 VKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDY---GDTVMYGLESSPCSWLR 164

  Fly   139 VFAPYIGTVVNTFLLIYQLGTCCVYVVFVASNIKAIVDAVADT--------------SIDVRLCM 189
            ..|.:...||:.||::.|||.||||.||:|.|.|.:::|...|              ::|.||.|
Human   165 NHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNETVILTPTMDSRLYM 229

  Fly   190 IIILLPLILINWVRNLKYLAPFSTLANAITMVSFGIICYYIFRE-------PVTTEGKDAFGKPS 247
            :..|..|:|:.::|||:.|:.||.|||...:||..:|..:|.:.       |:....|
Human   230 LSFLPFLVLLVFIRNLRALSIFSLLANITMLVSLVMIYQFIVQRIPDPSHLPLVAPWK------- 287

  Fly   248 NFPLFFGTVLFALEAIGVILPLENEMKTPQKFGGSCGVLNVSMVLIVFLYVGMGLFGYLNYGSAV 312
            .:||||||.:|:.|.||::|||||:||.|:||.   .:|.:.||::..||:.:|..|||.:|:.:
Human   288 TYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFP---LILYLGMVIVTILYISLGCLGYLQFGANI 349

  Fly   313 LGSITLNMPEHEVLSMCVKGMLAFAIYITHGLACYVAIDITWNDYVAKRLGAQRNALFWEYAVRT 377
            .||||||:| :..|...||.:.:..|:.|:.|..||..:|....:|::  ..:...|..:..|||
Human   350 QGSITLNLP-NCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIPFFVSR--APEHCELVVDLFVRT 411

  Fly   378 GLVLITFLLAVAIPNLELFISLFGALCLSALGLAFPALIQICTHWYNTKGFAKVWLVLSNFVLII 442
            .||.:|.:||:.||.|:|.|||.|::..|||.|..|.|:::.|  :.::|.:.: .:..:.::.|
Human   412 VLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLEVTT--FYSEGMSPL-TIFKDALISI 473

  Fly   443 VGILGLVIGTYTSLKEIV 460
            :|.:|.|:|||.:|.|::
Human   474 LGFVGFVVGTYEALYELI 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7888	NP_648425.1	SLC5-6-like_sbd	51..453	CDD:444915	153/447 (34%)
SLC36A1	XP_047272876.1	SLC5-6-like_sbd	78..484	CDD:444915	152/424 (36%)