DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7888 and Slc36a1

DIOPT Version :9

Sequence 1:	NP_648425.1	Gene:	CG7888 / 39232	FlyBaseID:	FBgn0036116	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_569099.1	Gene:	Slc36a1 / 155205	RGDID:	619801	Length:	475	Species:	Rattus norvegicus

Alignment Length:	473	Identity:	168/473 - (35%)
Similarity:	258/473 - (54%)	Gaps:	69/473 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 KDPDYNPYHHRDV---EHPT---------------TNS-----ETLFHLLKGSLGTGILAMPNAF 78
            ::.||:.|...||   |.|:               .||     :||.|||||::|||:|.:|.|.
  Rat     7 RNEDYHDYSSTDVSPEESPSEGLGSFSPGSYQRLGENSSMTWFQTLIHLLKGNIGTGLLGLPLAV 71

  Fly    79 RNSGYITGSIGTIVIGFICTFCIHQLVKAQYELCRRKKMPSMNYPMVAETAMGEGPKC-----FR 138
            :|:|.:.|.:..:|||.:...|:..|||..:.||||...|.::|   .:|.| .|.:|     .|
  Rat    72 KNAGLLLGPLSLLVIGIVAVHCMGILVKCAHHLCRRLNKPFLDY---GDTVM-YGLECSPSTWIR 132

  Fly   139 VFAPYIGTVVNTFLLIYQLGTCCVYVVFVASNIKAIVDAVADT--------------SIDVRLCM 189
            ..:.:...:|:.||::.|||.||||.||:|.|.|.:::|...|              ::|.||.|
  Rat   133 NHSHWGRRIVDFFLVVTQLGFCCVYFVFLADNFKQVIEAANGTTTNCNNNETVILTPTMDSRLYM 197

  Fly   190 IIILLPLILINWVRNLKYLAPFSTLANAITMVSFGIICYYIFRE-------PVTTEGKDAFGKPS 247
            :..|..|:|::::|||:.|:.||.|||....||..:|..:|.:.       |:....|
  Rat   198 LTFLPFLVLLSFIRNLRILSIFSLLANISMFVSLIMIYQFIVQRIPDPSHLPLVAPWK------- 255

  Fly   248 NFPLFFGTVLFALEAIGVILPLENEMKTPQKFGGSCGVLNVSMVLIVFLYVGMGLFGYLNYGSAV 312
            .:||||||.:||.|.|||:|||||:||..|||.   .:|.:.|.:|..||:.:|..|||.:|:.:
  Rat   256 TYPLFFGTAIFAFEGIGVVLPLENKMKDSQKFP---LILYLGMAIITVLYISLGSLGYLQFGADI 317

  Fly   313 LGSITLNMPEHEVLSMCVKGMLAFAIYITHGLACYVAIDITWNDYVAKRLGAQRNALFWEYAVRT 377
            .||||||:| :..|...||.:.:..|:.|:.|..|||.:|.....|::  ..:|..|..:.:.||
  Rat   318 KGSITLNLP-NCWLYQSVKLLYSIGIFFTYALQFYVAAEIIIPAIVSR--VPERFELVVDLSART 379

  Fly   378 GLVLITFLLAVAIPNLELFISLFGALCLSALGLAFPALIQICTHWYNTKGFAKVWLVLSNFVLII 442
            .:|.:|.:|||.||.|:|.|||.|::..|||.|..|.|:::.|  |..:|.:.: .:..:.::.|
  Rat   380 AMVCVTCVLAVLIPRLDLVISLVGSVSSSALALIIPPLLEVTT--YYGEGISPL-TITKDALISI 441

  Fly   443 VGILGLVIGTYTSLKEIV 460
            :|.:|.|:|||.||.|::
  Rat   442 LGFVGFVVGTYESLWELI 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7888	NP_648425.1	SLC5-6-like_sbd	51..453	CDD:294310	157/447 (35%)
CG7888	NP_648425.1	SdaC	62..456	CDD:223884	153/419 (37%)
Slc36a1	NP_569099.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..32		7/24 (29%)
Slc36a1	NP_569099.1	SLC5-6-like_sbd	47..452	CDD:382020	154/424 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352569
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	321	1.000	Inparanoid score	I2430
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	1	1.000	-	-		mtm8993
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22950
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X121
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.910