DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7888 and slc38a5a

DIOPT Version :9

Sequence 1:	NP_648425.1	Gene:	CG7888 / 39232	FlyBaseID:	FBgn0036116	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	XP_001344749.1	Gene:	slc38a5a / 100005797	ZFINID:	ZDB-GENE-081105-92	Length:	491	Species:	Danio rerio

Alignment Length:	540	Identity:	110/540 - (20%)
Similarity:	193/540 - (35%)	Gaps:	155/540 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPVMTKNGHSNSAYVADHPDKLE--------LAEKGQKNKAVVAKDPDYNPYHHRDVEHPTTNSE 57
            ||    |||.      |.|..||        |....:.::.:.:|..........|.|..|:...
Zfish     7 MP----NGHH------DIPMNLEKEFTGFDALENMAEGDQFLSSKSNGKIETQFTDFEGKTSFGM 61

  Fly    58 TLFHLLKGSLGTGILAMPNAFRNSGYITGSIGTIVIGFICTFCIHQLVKAQYELCRRKKMPSMNY 122
            ::|:|....:|:|||.:..|..|:|.|......|.|..:.::.||.|:::...:..|.      |
Zfish    62 SIFNLSNAIMGSGILGLAYAMANTGIILFVFLLITIALLSSYSIHLLLRSAGVVGIRA------Y 120

  Fly   123 PMVAETAMGEGPKCFRVFAPYIGTVVNTFLLIYQLGTCCVYVVFVASNIKAIVDAVA---DTS-- 182
            ..:...|.|...|          .|....:.::.:|....|:..|...:..:::.:.   |.|
Zfish   121 EQLGYRAFGTPGK----------VVAGCIITLHNIGAMSSYLFIVKIELPHVIEGLTGLPDNSGH 175

  Fly   183 --IDVRLCMII----ILLPLILINWVRNLKYLAPFS----------------------------- 212
              :|.|..:||    ::.||.|:..:..|.|.:.||
Zfish   176 WYVDGRYLIIIVSVCVIFPLALMKRLGYLGYTSGFSLSCMVFFLISVIYKCLSNSGIDSESNQNE 240

  Fly   213 --TLANAITMVSFGI----------ICYYIFREPVTTEGKDAFGKPSNFPLFFGTVLFALEAIGV 265
              |.:|| :|:|...          ||.   .:.:|...:.||..|        .:.||......
Zfish   241 KCTFSNA-SMISSTTEINEINSTTEICE---AKLLTINPQTAFTIP--------IIAFAFVCHPE 293

  Fly   266 ILPLENEMKTP-----QKFGGSCGVLNVSMVLIVFLYVGMGLFGYLNYGSAVLGSITLNMPEHEV 325
            :||:..|:|.|     ||      |.|:|::.:..:|:...:||||.:.:.|...:.....::::
Zfish   294 VLPIYTELKNPSKKQMQK------VANISILAMFVMYLLTAIFGYLTFFANVDSELLKMYNKNDI 352

  Fly   326 LSMCVKGMLAFAIYITHGLACYVAIDITWNDYVAKRLGAQRNALF----------W--EYAVRTG 378
            |.:||:            ||..||:.:|    |...|...|.|:.          |  ...:...
Zfish   353 LMLCVR------------LAVLVAVTLT----VPVVLFPIRRAVLQLLFPEKPFSWVRHIIIAMC 401

  Fly   379 LVLITFLLAVAIPNLELFISLFGALCLSALGLAFPALI----------------QICTHWYNTKG 427
            |:....||.:.:||:.......||....:|....|.:.                :|....:.|.|
Zfish   402 LLFAVNLLVIFVPNIRDIFGFIGATSAPSLIFILPGIFYIYIVPEEQEPLKSRPKILAILFVTLG 466

  Fly   428 FAKVWLVLSNFVLIIVGILG 447
            |  :::::|...:||..:.|
Zfish   467 F--IFMIMSITFIIIEWVNG 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7888	NP_648425.1	SLC5-6-like_sbd	51..453	CDD:294310	97/482 (20%)
CG7888	NP_648425.1	SdaC	62..456	CDD:223884	95/471 (20%)
slc38a5a	XP_001344749.1	SdaC	55..479	CDD:223884	94/475 (20%)
slc38a5a	XP_001344749.1	SLC5-6-like_sbd	55..479	CDD:294310	94/475 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594588
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840