Protein Alignment CG43693 and AVT4

DIOPT Version :10

• Sequence 1: NP_001261694.1
• Gene: CG43693 / 39231
• FlyBaseID: FBgn0263776
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_014298.1
• Gene: AVT4 / 855622
• SGDID: S000005045
• Length: 713
• Species: Saccharomyces cerevisiae
• Alignment Length: 620
• Identity: 157/620 - (25%)
• Similarity: 262/620 - (42%)
• Gaps: 128/620 - (20%)

  Fly     4 PENLNAPAGKPPLPPRREQLTEKGQSLSLSSFGGSAGNISGSGRKQHLSGAALARHKL------- 61
            |:.|..|.....:.|:.|..|:      |||..|.  |:.|..|::.:.......|:|
Yeast   157 PKRLRRPRSMENVTPKIEHHTK------LSSASGL--NVPGGFRREFIVNKKRQEHQLNDSASSD 213

  Fly    62 -----KMSLKRGGPPPVATSGSGVMTTSLDQQKIPTVTAGYGENEKPKGGKGGQS---KFIRSDM 118
                 ..|:.:..|           :::.|..|:|.:|..:.|.....|...|:|   .|| .|.
Yeast   214 FTSHESDSINQSSP-----------SSNQDIDKVPFLTRNFLEFLYVFGHFAGESFEDDFI-PDS 266

  Fly   119 ADVPVQQAAGSTLPLVISRKKGDDSEDGNYNPFEHRKV----EHPTSDLETFVHLLKGSLGSGIL 179
            :::.:               :|:|......:..:|.||    :..||..:.|:.|||..:|:|:|
Yeast   267 SNMMI---------------RGEDERSALLSRPDHMKVLPSAKGTTSTKKVFLILLKSFIGTGVL 316

  Fly   180 AMPMAFSHAGLWFGLVATFAVGTLCTYCVHILVKCAHILCRRRKIPMMGFADVAEQAFLDGPPAL 244
            .:|.||.:.||:|.:......|....:|.:|||:.      :....:..|.|:..:.:  ||
Yeast   317 FLPNAFHNGGLFFSVSMLAFFGIYSYWCYYILVQA------KSSCGVSSFGDIGLKLY--GP--- 370

  Fly   245 NRWSRFIRFMVNTFLVIDLLGCCCIYLVFVATN----VEQVVRVYMETELSIRVWIMIVTAPLIF 305
              |.|.|   :...|||..:|....|::|.|.|    ::.|..|.:.....:.|:..|:..||.|
Yeast   371 --WMRII---ILFSLVITQVGFSGAYMIFTAKNLQAFLDNVFHVGVLPLSYLMVFQTIIFIPLSF 430

  Fly   306 MCLVRNLKFLTPFSMIANILMFVGIVITFIY----MFSDI---PAPVERPGIV---SVTEWPLFF 360
               :||:..|:..|::||..:..|:||..|:    :|.|:   ||    .|:|   :...|.||.
Yeast   431 ---IRNISKLSLPSLLANFFIMAGLVIVIIFTAKRLFFDLMGTPA----MGVVYGLNADRWTLFI 488

  Fly   361 GTVIFALEGIGVVMSLENDMKNPSHFIGCPSVLNFGMGLVIALYTLVGFFGFLKYGPETQASITL 425
            ||.|||.||||:::.:::.|:||..|   |.||...:.....|:..:...|:|.||...|..|.|
Yeast   489 GTAIFAFEGIGLIIPVQDSMRNPEKF---PLVLALVILTATILFISIATLGYLAYGSNVQTVILL 550

  Fly   426 NLPLEDKLAQSVKLMIAIAIFFTFTLQFYVPVTILWKGLEHK--------------------IRP 470
            |||..:.....::|..:|||..:..||.:..:.|    :|:|                    :||
Yeast   551 NLPQSNIFVNLIQLFYSIAIMLSTPLQLFPAIKI----IENKFFPKFTKIYVKHDDLTTRVELRP 611

  Fly   471 EKQNIS------EYGLRVFLVLLCGGIA-VALPNLGPFISLIGAVCLSTLGMIVPATIELAVYHE 528
            ....::      :..:|..:|::...|| ....||..|:|:||::....|..|.|:.:.|.....
Yeast   612 NSGKLNWKIKWLKNFIRSIIVIIVVSIAYFGSDNLDKFVSVIGSLACIPLVYIYPSMLHLRGNSL 676

  Fly   529 DPGYGRFNWRL--WKNSGLILFGVVGFVAGTYVSI 561
            ....|.| ||.  ..::.||.||:...:..:|.||
Yeast   677 PETKGEF-WRFKPMLDTILIFFGIASMLYTSYQSI 710

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43693	NP_001261694.1	SLC5-6-like_sbd	158..562	CDD:444915	124/447 (28%)
AVT4	NP_014298.1	Aa_trans	295..711	CDD:279788	124/447 (28%)