DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG43693 and LHT7

DIOPT Version :9

Sequence 1:	NP_001261694.1	Gene:	CG43693 / 39231	FlyBaseID:	FBgn0263776	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	NP_567977.2	Gene:	LHT7 / 829671	AraportID:	AT4G35180	Length:	478	Species:	Arabidopsis thaliana

Alignment Length:	575	Identity:	135/575 - (23%)
Similarity:	212/575 - (36%)	Gaps:	182/575 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 SLKRGGPPPVATSGSGVMTTSLDQQKIPTVTAGYGENEKPKGGKGGQSKFIRSDMADVPVQQAAG 128
            |.:.||.|...:.     ..|.|.|.|        ..|| .||.||:          :||::
plant    13 SQESGGSPLFMSP-----APSTDPQPI--------SGEK-NGGDGGR----------IPVEE--- 50

  Fly   129 STLPLVISRKKGDDSEDGN-YNPFEHRKVEHPTSDLETFVHLLKGSLGSGILAMPMAFSHAG-LW 191
             .||:..|||       || |.              .|| |||...:|..::.:|.||:..| :|
plant    51 -WLPITESRK-------GNVYT--------------ATF-HLLCSGIGLQVILLPAAFAALGWVW 92

  Fly   192 FGLVATFAVGTLC-TYCVHILVKCAHILCRRRKIPMMGFADVAEQAFLDGPPALNRWSRFIRFMV 255
            ..::.|  ||.:. .|...:||: .|                      :..|.: |.||::|..:
plant    93 GTIILT--VGFVWKLYTTWLLVQ-LH----------------------EAVPGI-RISRYVRLAI 131

  Fly   256 NTFLVI--DLL----------GCCCIYLVFVATNVEQVVRVYMETELSIRVWIMIVTAP------ 302
            .:|.|.  .||          |.|.|.::....:::|::::..:..          |||
plant   132 ASFGVKLGKLLGIFPVMYLSGGACTILVITGGKSIQQLLQIMSDDN----------TAPLTSVQC 186

  Fly   303 -LIFMCLVR------NLKFLTPFSMIANILMFVGIVITFIYMFSDIPAPVERPGI-VSVTEWPLF 359
             |:|.|:..      ||..|...|:|.   .|:||....:.....:.:..:|..: ||.......
plant   187 FLVFSCIAMIMSQFPNLNSLFGVSLIG---AFMGIAYCTVIWILPVASDSQRTQVSVSYATMDKS 248

  Fly   360 F-------GTVIFALEGIGVVM----SLENDMKNPSHFIGCPSVLNFGM---GLV-IALYTLVGF 409
            |       |.:.....|..:|:    :|.:|.||||    |.::....|   .|| |.::.|. |
plant   249 FVHIFNAIGLIALVYRGNNLVLEIQGTLPSDSKNPS----CKTMWRAVMISHALVAICMFPLT-F 308

  Fly   410 FGFLKYG---PETQASITLNLPLEDKLAQSVKLMIAIAIFFTFTLQFYVPVTIL--WKGLEHKIR 469
            ..:..||   |.|...:...|.|..: ..|.:....|.:.|.|:.....|:.::  ...:|....
plant   309 AVYWAYGDKIPATGGPVGNYLKLYTQ-EHSKRAACFIHLTFIFSCLCSYPINLMPACDNIEMVYI 372

  Fly   470 PEKQN----ISEYGLRVFLVLLCGGIAVALPNLGPFIS-LIGAVCLSTLGMIVPATIELAVYHED 529
            .:|:.    |....|||||.|:|..|||..|.| |::: ||||:.|     :|..|
plant   373 TKKKKPASIIVRMMLRVFLSLVCFTIAVGFPFL-PYLAVLIGAIAL-----LVTFT--------- 422

  Fly   530 PGYGRFNW----RLWKNSGLILFGVVGFVAGTYVSII------------EFHAEF 568
              |..|.|    :..:.|.:.||.|:....|..:|::            ..||.|
plant   423 --YPCFMWISIKKPQRKSPMWLFNVLVGCLGASLSVLLLVASAMRLAQKGLHANF 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43693	NP_001261694.1	SdaC	153..561	CDD:223884	107/464 (23%)
CG43693	NP_001261694.1	SLC5-6-like_sbd	158..562	CDD:294310	108/460 (23%)
LHT7	NP_567977.2	SLC5-6-like_sbd	58..462	CDD:294310	113/487 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D464614at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910