DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43693 and slc32a1

DIOPT Version :9

Sequence 1:	NP_001261694.1	Gene:	CG43693 / 39231	FlyBaseID:	FBgn0263776	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	NP_001074170.1	Gene:	slc32a1 / 798575	ZFINID:	ZDB-GENE-061201-1	Length:	530	Species:	Danio rerio

Alignment Length:	570	Identity:	131/570 - (22%)
Similarity:	222/570 - (38%)	Gaps:	117/570 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 AALARHKLKMSLKRGGPPPVATSGSGVMTTSLDQQKIPTVTAGYG-------------------- 98
            |.|.|.|:...|          |.:....|:..|.|:..:.|..|
Zfish     2 ATLIRSKISNKL----------SNAATTVTNKSQAKVSGMFARLGFQAATDEEALGFAACDDLDY 56

  Fly    99 -----------ENEKPKGGKGGQSKFIRSDMADVPVQ-QAAGSTLPLVISRKKGDDSEDGNYNPF 151
                       :|:: .||:|| .:.....||:.... |..|:..|...|:..|..||.|  ||.
Zfish    57 DHRQGLQMDILKNDE-MGGEGG-GEMGEDGMAEGDSHYQRDGTGPPPSASKDGGLCSEIG--NPD 117

  Fly   152 EHRKVEHPTSDLETFVHLLKGSLGSGILAMPMAFSHAGLWFGLVATFAVGTLCTYCVHILVKCAH 216
            :.|     .:..|...::.....|..:|.:|.|..|.| :.||........:|.|...||:.|.:
Zfish   118 KPR-----ITAWEAGWNVTNAIQGMFVLGLPYAILHGG-YLGLFLIIFAAVVCCYTGKILIACLY 176

  Fly   217 ------ILCRRRKIPMMGFADVAEQAFLDGPPALNRWSRFIRFMVNTFLVIDLLGCCCIYLVFVA 275
                  .|.|.|.    .:.|:|........|||.      ..:||...:|:|:..|.:|:| |:
Zfish   177 EENEDGQLVRVRD----SYVDIANACCAPRFPALG------GHVVNVAQIIELVMTCILYVV-VS 230

  Fly   276 TNVEQVVRVYMETELSIRVWIMIVTAPLIFMCLVRNLKFLTPFSMIANILMFVGIVITFIYMFSD 340
            .|:  :...:....:|.|.|.:|.||.|:....::|||.::.||::..:..||..::...|..|.
Zfish   231 GNL--MYNSFPTLPVSQRSWAIIATAALLPCAFLKNLKAVSKFSLLCTLAHFVINILVIAYCLSR 293

  Fly   341 IP--APVERPGIVSVTEWPLFFGTVIFALEGIGVVMSLENDMKNPSHFIGCPSVLNFGMGLVIAL 403
            ..  |..:....:.|.::|:..|.::|:......:.|||.:|:.||.|....:..:....::..|
Zfish   294 ARDWAWDKVKFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQKPSEFHCMMNWTHIAACILKGL 358

  Fly   404 YTLVGFFGFLKYGPETQASITLNLPLEDKLAQSVKLMIAIAIFFTFTLQFYVPVTILWK------ 462
            :.||   .:|.:..||:..||.|||  ..:...|.|.:......::.|.|:..|.:|.|
Zfish   359 FALV---AYLTWADETKEVITDNLP--SSIRAVVNLFLVSKALLSYPLPFFAAVEVLEKTFFQDG 418

  Fly   463 ---------GLEHKIRPEKQNISEYG--LRVFLVLLCGGIAVALPNLGPFISLIGAVCLSTLGMI 516
                     |.:.:::       .:|  ||..||:....:|:.:|:....:.|.|::..:.|..:
Zfish   419 GRAFFPDCYGGDGRLK-------SWGLSLRCALVVFTMLMAIYVPHFALLMGLTGSLTGAGLCFL 476

  Fly   517 VPATIELAVYHEDPGYGRFNWR--LWKNSGLILFGVVGFVAGTYVSIIEF 564
            :|:...|          :..||  ||..   :.|.|..||.|...||..|
Zfish   477 LPSLFHL----------KLLWRKLLWHQ---VFFDVAIFVIGGICSISGF 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43693	NP_001261694.1	SdaC	153..561	CDD:223884	100/434 (23%)
CG43693	NP_001261694.1	SLC5-6-like_sbd	158..562	CDD:294310	100/430 (23%)
slc32a1	NP_001074170.1	Aa_trans	120..517	CDD:279788	103/438 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810