Protein Alignment CG43693 and SLC38A4

DIOPT Version :10

• Sequence 1: NP_001261694.1
• Gene: CG43693 / 39231
• FlyBaseID: FBgn0263776
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_060488.2
• Gene: SLC38A4 / 55089
• HGNCID: 14679
• Length: 547
• Species: Homo sapiens
• Alignment Length: 609
• Identity: 130/609 - (21%)
• Similarity: 222/609 - (36%)
• Gaps: 187/609 - (30%)

  Fly    63 MSLKRGGPPPVATSGSGVMTTSLDQQKIPTVTAGYGENEKPKGGKGGQSKFIRSDMADVPVQQAA 127
            |.|:.....|...|.||        :..|....|.|.:||    ....|:|...|...   |:..
Human     4 MELRNVNIEPDDESSSG--------ESAPDSYIGIGNSEK----AAMSSQFANEDTES---QKFL 53

  Fly   128 GSTLPLVISRKKGDDSEDGNYNPFEHRKVEHP--TSDLETFVHLLKGSLGSGILAMPMAFSHAGL 190
            .:..   :.:||..|..|      ||    ||  ||...:..:|....:|||||.:..|.::.|:
Human    54 TNGF---LGKKKLADYAD------EH----HPGTTSFGMSSFNLSNAIMGSGILGLSYAMANTGI 105

  Fly   191 WFGLVATFAVGTLCTYCVHILVKCAHILCRRRKIPMMGFADVAEQAFLDGPPALNRWSRFIRFMV 255
            ...::...||..|..|.||:|:|.|      ::...:.:..:.|:||  |.|.          .:
Human   106 ILFIIMLLAVAILSLYSVHLLLKTA------KEGGSLIYEKLGEKAF--GWPG----------KI 152

  Fly   256 NTFLVIDL--LGCCCIYLVFVATNVEQVVRVYMETELSIRVW-------IMIVTAPLIF-MCLVR 310
            ..|:.|.:  :|....||..:...:.:|:|.:|..|.:...|       |:.|:..:|. :.|::
Human   153 GAFVSITMQNIGAMSSYLFIIKYELPEVIRAFMGLEENTGEWYLNGNYLIIFVSVGIILPLSLLK 217

  Fly   311 NLKFL---TPFSMIANILMFVGIVITFIYMFSDIPAPVERPGIVSVTEWPLFFGTVI-------- 364
            ||.:|   :.||:.. ::.||.:|   ||....||.|:.   ::..:...|.|...:
Human   218 NLGYLGYTSGFSLTC-MVFFVSVV---IYKKFQIPCPLP---VLDHSVGNLSFNNTLPMHVVMLP 275

  Fly   365 ----------------------------FALEGIGVVMSLENDMK-NPSHFI------------- 387
                                        .:|...||.....:|.| .|.:|:
Human   276 NNSESSDVNFMMDYTHRNPAGLDENQAKGSLHDSGVEYEAHSDDKCEPKYFVFNSRTAYAIPILV 340

  Fly   388 ---GC-PSVL------------------NFGMGLVIALYTLVGFFGFLKYGPETQASI------- 423
               .| |.||                  |..:..::.:|.|...||:|.:..|.:..:
Human   341 FAFVCHPEVLPIYSELKDRSRRKMQTVSNISITGMLVMYLLAALFGYLTFYGEVEDELLHAYSKV 405

  Fly   424 -TLNLPLEDKLAQSVKLMIAIAIFFTFTLQFYVP----------VTILWKGLEHKIRPEK--QNI 475
             ||::||         ||:.:|:....||.  ||          :|:|:        |::  ..|
Human   406 YTLDIPL---------LMVRLAVLVAVTLT--VPIVLFPIRTSVITLLF--------PKRPFSWI 451

  Fly   476 SEYGLRVFLVLLCGGIAVALPNLGPFISLIGAVCLSTLGMIVPATIELAVYHEDPGYGRFNWRLW 540
            ..:.:...|:.|...:.:.:|.:......|||...:.|..|:||...|.:..::      .:|..
Human   452 RHFLIAAVLIALNNVLVILVPTIKYIFGFIGASSATMLIFILPAVFYLKLVKKE------TFRSP 510

  Fly   541 KNSGLILFGVVG--FVAGTYVSII 562
            :..|.::|.|||  |:.|:...||
Human   511 QKVGALIFLVVGIFFMIGSMALII 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43693	NP_001261694.1	SLC5-6-like_sbd	158..562	CDD:444915	107/512 (21%)
SLC38A4	NP_060488.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..30		7/33 (21%)
		SLC5-6-like_sbd	73..535	CDD:444915	107/512 (21%)