Protein Alignment CG43693 and SLC38A4

DIOPT Version :9

• Sequence 1: NP_001261694.1
• Gene: CG43693 / 39231
• FlyBaseID: FBgn0263776
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_001137296.1
• Gene: SLC38A4 / 55089
• HGNCID: 14679
• Length: 547
• Species: Homo sapiens
• Alignment Length: 607
• Identity: 130/607 - (21%)
• Similarity: 221/607 - (36%)
• Gaps: 183/607 - (30%)

  Fly    63 MSLKRGGPPPVATSGSGVMTTSLDQQKIPTVTAGYGENEKPKGGKGGQSKFIRSDMADVPVQQAA 127
            |.|:.....|...|.||        :..|....|.|.:||    ....|:|...|...   |:..
Human     4 MELRNVNIEPDDESSSG--------ESAPDSYIGIGNSEK----AAMSSQFANEDTES---QKFL 53

  Fly   128 GSTLPLVISRKKGDDSEDGNYNPFEHRKVEHP--TSDLETFVHLLKGSLGSGILAMPMAFSHAGL 190
            .:..   :.:||..|..|      ||    ||  ||...:..:|....:|||||.:..|.::.|:
Human    54 TNGF---LGKKKLADYAD------EH----HPGTTSFGMSSFNLSNAIMGSGILGLSYAMANTGI 105

  Fly   191 WFGLVATFAVGTLCTYCVHILVKCAHILCRRRKIPMMGFADVAEQAFLDGPPALNRWSRFIRFMV 255
            ...::...||..|..|.||:|:|.|      ::...:.:..:.|:||  |.|.          .:
Human   106 ILFIIMLLAVAILSLYSVHLLLKTA------KEGGSLIYEKLGEKAF--GWPG----------KI 152

  Fly   256 NTFLVIDL--LGCCCIYLVFVATNVEQVVRVYMETELSIRVW-------IMIVTAPLIF-MCLVR 310
            ..|:.|.:  :|....||..:...:.:|:|.:|..|.:...|       |:.|:..:|. :.|::
Human   153 GAFVSITMQNIGAMSSYLFIIKYELPEVIRAFMGLEENTGEWYLNGNYLIIFVSVGIILPLSLLK 217

  Fly   311 NLKFL---TPFSMIANILMFVGIVITFIYMFSDIPAPVERPGIVSVTEWPLFFGTVI-------- 364
            ||.:|   :.||:.. ::.||.:|   ||....||.|:.   ::..:...|.|...:
Human   218 NLGYLGYTSGFSLTC-MVFFVSVV---IYKKFQIPCPLP---VLDHSVGNLSFNNTLPMHVVMLP 275

  Fly   365 ----------------------------FALEGIGVVMSLENDMK-NPSHFI------------- 387
                                        .:|...||.....:|.| .|.:|:
Human   276 NNSESSDVNFMMDYTHRNPAGLDENQAKGSLHDSGVEYEAHSDDKCEPKYFVFNSRTAYAIPILV 340

  Fly   388 ---GC-PSVL------------------NFGMGLVIALYTLVGFFGFLKYGPETQASI------- 423
               .| |.||                  |..:..::.:|.|...||:|.:..|.:..:
Human   341 FAFVCHPEVLPIYSELKDRSRRKMQTVSNISITGMLVMYLLAALFGYLTFYGEVEDELLHAYSKV 405

  Fly   424 -TLNLPLEDKLAQSVKLMIAIAIFFTFTLQFYVPVTILWKGLEHKIR--------PEK--QNISE 477
             ||::||         ||:.:|:....||.  ||:.:.      .||        |::  ..|..
Human   406 YTLDIPL---------LMVRLAVLVAVTLT--VPIVLF------PIRTSVITLLFPKRPFSWIRH 453

  Fly   478 YGLRVFLVLLCGGIAVALPNLGPFISLIGAVCLSTLGMIVPATIELAVYHEDPGYGRFNWRLWKN 542
            :.:...|:.|...:.:.:|.:......|||...:.|..|:||...|.:..::      .:|..:.
Human   454 FLIAAVLIALNNVLVILVPTIKYIFGFIGASSATMLIFILPAVFYLKLVKKE------TFRSPQK 512

  Fly   543 SGLILFGVVG--FVAGTYVSII 562
            .|.::|.|||  |:.|:...||
Human   513 VGALIFLVVGIFFMIGSMALII 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43693	NP_001261694.1	SdaC	153..561	CDD:223884	108/514 (21%)
		SLC5-6-like_sbd	158..562	CDD:294310	107/510 (21%)
SLC38A4	NP_001137296.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..30		7/33 (21%)
		SdaC	71..534	CDD:223884	107/510 (21%)
		SLC5-6-like_sbd	73..535	CDD:294310	107/510 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820