Protein Alignment CG43693 and SLC38A2

DIOPT Version :9

• Sequence 1: NP_001261694.1
• Gene: CG43693 / 39231
• FlyBaseID: FBgn0263776
• Length: 572
• Species: Drosophila melanogaster
• Sequence 2: NP_061849.2
• Gene: SLC38A2 / 54407
• HGNCID: 13448
• Length: 506
• Species: Homo sapiens
• Alignment Length: 541
• Identity: 109/541 - (20%)
• Similarity: 195/541 - (36%)
• Gaps: 155/541 - (28%)

  Fly   122 PVQQAAGSTLPLVISRKKGDDSEDGNY---NPFEHRKVE---HP--TSDLETFVHLLKGSLGSGI 178
            |.:|||      :.|.....|.|:.|:   :....:|.|   ||  ||...:..:|....:||||
Human    31 PTKQAA------LKSHYADVDPENQNFLLESNLGKKKYETEFHPGTTSFGMSVFNLSNAIVGSGI 89

  Fly   179 LAMPMAFSHAGLWFGLVATFAVGTLCTYCVHILVKCAH----ILCRRRKIPMMGFADVAEQAF-L 238
            |.:..|.::.|:...::....|.....|.||:|:|.|:    :|          :..:..:|| |
Human    90 LGLSYAMANTGIALFIILLTFVSIFSLYSVHLLLKTANEGGSLL----------YEQLGYKAFGL 144

  Fly   239 DGPPALNRWSRFIRFMVNTFLVIDLLGCCCIYLVFVATNVEQVVRVYMETELSIRVW-------I 296
            .|           :...:..:.:..:|....||..|...:..|::.....|....:|       :
Human   145 VG-----------KLAASGSITMQNIGAMSSYLFIVKYELPLVIQALTNIEDKTGLWYLNGNYLV 198

  Fly   297 MIVTAPLIF-MCLVRNLKFLTPFSMIANILMFVGIVITFIYMFSDIPAPVERPGIVSVTEWPLFF 360
            ::|:..:|. :.|.|||.:|...|.::.:.|...:::.....| .:|.|||...|::.|     .
Human   199 LLVSLVVILPLSLFRNLGYLGYTSGLSLLCMVFFLIVVICKKF-QVPCPVEAALIINET-----I 257

  Fly   361 GTVIFALEGIGVVMS---LENDMKNPSHFI----------------GC-PSVLN----------- 394
            .|.:.....:...:|   .|||...|.:||                .| |:||.
Human   258 NTTLTQPTALVPALSHNVTENDSCRPHYFIFNSQTVYAVPILIFSFVCHPAVLPIYEELKDRSRR 322

  Fly   395 ----------FGMGLVIALYTLVGFFGFLKYGPETQASI--TLNLPL-EDKLAQSVKLMIAIAIF 446
                      |.|.|   :|.|...||:|.:....::.:  |.:..| .|.|...|:|.:.:|:.
Human   323 RMMNVSKISFFAMFL---MYLLAALFGYLTFYEHVESELLHTYSSILGTDILLLIVRLAVLMAVT 384

  Fly   447 FTFTLQFYVPVTILWKGLEHKIRPEKQNISEYGLRVFLVLLCGG--------------------- 490
            .|      |||.|.         |.:.:::.        |||..
Human   385 LT------VPVVIF---------PIRSSVTH--------LLCASKDFSWWRHSLITVSILAFTNL 426

  Fly   491 IAVALPNLGPFISLIGAVCLSTLGMIVPATIELAVYHEDPGYGRFNWRLWKNSGLILF---GVVG 552
            :.:.:|.:......|||...|.|..|:|:...:.:..::|      .:..:..|.:.|   ||:.
Human   427 LVIFVPTIRDIFGFIGASAASMLIFILPSAFYIKLVKKEP------MKSVQKIGALFFLLSGVLV 485

  Fly   553 FVAGTYVSIIEF-HAEFSSGH 572
            ......:.:::: |.....||
Human   486 MTGSMALIVLDWVHNAPGGGH 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43693	NP_001261694.1	SdaC	153..561	CDD:223884	98/493 (20%)
		SLC5-6-like_sbd	158..562	CDD:294310	96/486 (20%)
SLC38A2	NP_061849.2	Regulates protein turnover upon amino acid deprivation. /evidence=ECO:0000250	1..96		20/70 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..23
		SLC5-6-like_sbd	69..495	CDD:320982	94/484 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820