DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43693 and CG32079

DIOPT Version :9

Sequence 1:	NP_001261694.1	Gene:	CG43693 / 39231	FlyBaseID:	FBgn0263776	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	NP_729645.3	Gene:	CG32079 / 39230	FlyBaseID:	FBgn0052079	Length:	457	Species:	Drosophila melanogaster

Alignment Length:	448	Identity:	154/448 - (34%)
Similarity:	250/448 - (55%)	Gaps:	20/448 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 VQQAAGSTLPLVISRKKGDDSEDGNYNPFEHRKVEHPTSDLETFVHLLKGSLGSGILAMPMAFSH 187
            ||.:.||  ||....:.....::|             .||||.|:::||...|:|.||||.||.:
  Fly    23 VQNSFGS--PLANEARLSSKKDNG-------------MSDLEAFINVLKCGFGTGCLAMPYAFLN 72

  Fly   188 AGLWFGLVATFAVGTLCTYCVHILVKCAHILCRRRKIPMMGFADVAEQAFLDGPPALNRWSRFIR 252
            :|...||:.|||:|....|.:|||:...:.|..:..:||:.:....|.:...||...:..|:...
  Fly    73 SGWLVGLICTFALGFFVLYAMHILLHHINNLGVQHNMPMISYRKAVELSIRKGPSIFHFLSKPFG 137

  Fly   253 FMVNTFLVIDLLGCCCIYLVFVATNVEQVVRVYMETELSIRVWIMIVTAPLIFMCLVRNLKFLTP 317
            ::|:..|.....|..|:|:||:|.:::.:..:|:.. ...|:::.::.:|||...|:||||.|.|
  Fly   138 YLVDILLCAYHFGVDCVYVVFIAKSLKHLGDMYLWV-WDERLYMALIASPLILTFLIRNLKSLVP 201

  Fly   318 FSMIANILMFVGIVITFIYMFSDIPAPVERPGIVSVTEWPLFFGTVIFALEGIGVVMSLENDMKN 382
            ||:|:|||:..|..:...|:|.|:|.......|..:..:|:|||||:|::|.:||::||...|:.
  Fly   202 FSIISNILLLTGYCVILNYLFRDLPEFEHLHAIQPLRNFPIFFGTVLFSIESVGVILSLGRSMRK 266

  Fly   383 PSHFIGCPSVLNFGMGLVIALYTLVGFFGFLKYGPETQASITLNLPLEDKLAQSVKLMIAIAIFF 447
            |...:|...|||.||.:||:.|.:.||||:.:||..|..||..|:|..|.|.:....:.|:||||
  Fly   267 PESLMGTCGVLNQGMIVVISFYAVFGFFGYWRYGENTSNSILQNMPQNDILPKLATGIFALAIFF 331

  Fly   448 TFTLQFYVPVTILWKG-LEHKIRPEKQNISEYGLRVFLVLLCGGIAVALPNLGPFISLIGAVCLS 511
            ::.||.||.|.|:|:. ||.::........|..||:.||:....:|:..|:.|..:||:|:.||:
  Fly   332 SYALQGYVTVDIIWRNYLEPELEDRYLRTVECLLRIALVIASVLVAIQYPDFGLLLSLVGSFCLA 396

  Fly   512 TLGMIVPATIELAV-YHEDPGYGRFNWRLWKNSGLILFGVVGFVAGTYVSIIEFHAEF 568
            .||:|:|..:::.: |.||.|.|:.  .|.::...|..|:.|.||||.|::...:|.:
  Fly   397 QLGLILPGIVDICLRYEEDYGPGKI--FLIRSMLFICMGLAGGVAGTVVTLQTLYARY 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43693	NP_001261694.1	SdaC	153..561	CDD:223884	146/409 (36%)
CG43693	NP_001261694.1	SLC5-6-like_sbd	158..562	CDD:294310	146/405 (36%)
CG32079	NP_729645.3	SLC5-6-like_sbd	46..446	CDD:294310	146/402 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	157	1.000	Domainoid score	I1306
eggNOG	1	0.900	-	-		E1_COG0814
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1622
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	1	1.000	-	-		mtm1178
orthoMCL	1	0.900	-	-		OOG6_100466
Panther	1	1.100	-	-	P	PTHR22950
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X121
	11	10.880