DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43693 and slc-36.1

DIOPT Version :9

Sequence 1:	NP_001261694.1	Gene:	CG43693 / 39231	FlyBaseID:	FBgn0263776	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	NP_499743.2	Gene:	slc-36.1 / 259544	WormBaseID:	WBGene00012804	Length:	455	Species:	Caenorhabditis elegans

Alignment Length:	447	Identity:	156/447 - (34%)
Similarity:	251/447 - (56%)	Gaps:	10/447 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   125 QAAGSTLPLVISRKKGDDSEDGNYNPFEHR-KVEHPTSDLETFVHLLKGSLGSGILAMPMAFSHA 188
            :|.|.|  .|.:.::...|||.:.  |:.| ..|:..:..:.|:|::|..||:|:|::|:||.|:
Worm    17 EAPGDT--EVQTPRRNTVSEDTSL--FQDRLPTENSLTPEQAFIHMVKAMLGTGLLSLPLAFKHS 77

  Fly   189 GLWFGLVATFAVGTLCTYCVHILVKCAHILCRRRKIPMMGFADVAEQAFLDGPPALNRWSRFIRF 253
            ||:.||:.|..:..:|.||:..:|..||.:|.|....::.:|::...|...|||.:.|...|.:.
Worm    78 GLFLGLILTVLICLICLYCMRQVVFAAHFVCNRNGRDLIDYANIMRGAVEMGPPWIKRNGYFFKQ 142

  Fly   254 MVNTFLVIDLLGCCCIYLVFVATNVEQVVRVYMETELSIRVWIMIVTAPLIFMCLVRNLKFLTPF 318
            :||..:.|..||.||:|.||:|.|:|..........||..||::::..|::.:|.:|.|..|.||
Worm   143 LVNVNMFISQLGFCCVYFVFMADNLEDFFNNNTSIHLSKAVWMLLLLIPMLSICSIRRLSILAPF 207

  Fly   319 SMIANILMFVGIVITFIYMFSDIPAPVERPGIVSVTEWPLFFGTVIFALEGIGVVMSLENDMKNP 383
            :|.||::..|.:.:...:..||:......|.....|:.|||||||:||.||:.|:|.:||.|::|
Worm   208 AMAANVVYVVAVAVVLFFFLSDLRPISSLPWFGKATDLPLFFGTVMFAFEGVAVIMPIENRMQSP 272

  Fly   384 SHFIGCPSVLNFGMGLVIALYTLVGFFGFLKYGPETQASITLNLPLEDKLAQSVKLMIAIAIFFT 448
            ..||....|||....:|:|::::.||:|:|..|.:.:.:.|||||: ....|::|||....|..:
Worm   273 HAFISWNGVLNSSCLVVLAIFSVTGFYGYLSLGNDVKDTATLNLPM-TPFYQTIKLMFVACIMIS 336

  Fly   449 FTLQFYVPVTILWKGLEHKIRPEKQNISEYGLRVFLVLLCGGIAVALPNLGPFISLIGAVCLSTL 513
            :.||||||:..:.|.:..||..:||.:..|..|...|:|...||..:|:|..|||||||...:::
Worm   337 YPLQFYVPMERIEKWITRKIPVDKQTLYIYIARYSGVILTCAIAELIPHLALFISLIGAFSGASM 401

  Fly   514 GMIVPATIELAVYHEDPGYGRFNWRLW-KNSGLILFGVVGFVAGTYVSIIEFHAEFS 569
            .::.|..|||...:   .....:..|| ||..|:.|..:||..|||.::||....|:
Worm   402 ALLFPPCIELLTSY---AKNELSTGLWIKNIVLLTFAFIGFTTGTYSALIEIAKTFA 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43693	NP_001261694.1	SdaC	153..561	CDD:223884	145/409 (35%)
CG43693	NP_001261694.1	SLC5-6-like_sbd	158..562	CDD:294310	143/404 (35%)
slc-36.1	NP_499743.2	SLC5-6-like_sbd	50..445	CDD:382020	142/398 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	277	1.000	Domainoid score	I909
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H129128
Inparanoid	1	1.050	282	1.000	Inparanoid score	I1740
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	1	1.000	-	-		mtm4749
orthoMCL	1	0.900	-	-		OOG6_100466
Panther	1	1.100	-	-	O	PTHR22950
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R126
SonicParanoid	1	1.000	-	-		X121
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.910