DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43693 and Y32F6A.4

DIOPT Version :9

Sequence 1:	NP_001261694.1	Gene:	CG43693 / 39231	FlyBaseID:	FBgn0263776	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	NP_505680.2	Gene:	Y32F6A.4 / 179456	WormBaseID:	WBGene00012529	Length:	519	Species:	Caenorhabditis elegans

Alignment Length:	494	Identity:	111/494 - (22%)
Similarity:	202/494 - (40%)	Gaps:	106/494 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 STLPLVISRKKGDDSEDGNYNPFEHRKVE------HPTSDLETFVH--LLKGSL-GSGILAMPMA 184
            ||.....||:   ||.:|......|..|:      :| :.|..||.  .:.|.| |.||:|:|.|
Worm    19 STRTSSCSRR---DSWNGETRSSSHCDVDMSKPFFNP-AGLNWFVTGLFVVGDLAGGGIVALPTA 79

  Fly   185 FSHAGLWFGLVATFAVGTLCTYCVHILVKCAHIL----------CRRRKIPMMGFADVAEQAFLD 239
            ...|..|.||:....:..:.||..::|....:||          ||:      .:.::..:|.
Worm    80 IIQAEFWTGLIVCVILIGVVTYTAYVLGLSWNILLSTWPEYRHHCRK------PYPEIGGRAM-- 136

  Fly   240 GPPALNRWSRFIRFMVNTFLVIDLLGCCCIYLVFVATNVEQVVRVYMETELSIRVWIMIVTAPLI 304
                    .:..:.:|:..:.:.......:||:..:.|:..::..:..|.:|..:.|:||...|:
Worm   137 --------GKTCQLLVSICIDVTQFMISVVYLLLASKNIMNMIIAFSGTHISFCILILIVATCLL 193

  Fly   305 FMCLVRN---------LKFLTPFSMIANILMFVGIVITF--IYMFSDIPAPVERPGIVSVTEWPL 358
            .:|.:::         :..:|  :..|.||:.||.:|.:  ...|:.:|.       ...|...|
Worm   194 PLCFLKSPQDFWWAVVIAMMT--TSAAVILIIVGSIIDYGKCAPFAKLPP-------FRTTNLFL 249

  Fly   359 FFGTVIFALEGIGVVMSLENDMKNPSHFIGCPSVLNFGMGLVIALYTLVGFFGFLKYGPETQASI 423
            ..||::|::.|.....::::|||.|..|  ..||. ....::..:|..|...|:|.||...:.||
Worm   250 SMGTLLFSVGGHSAFPTIQHDMKQPKEF--TRSVF-LAFTIMAFMYIPVCIMGYLVYGDSLRDSI 311

  Fly   424 TLNLPLEDKLAQSVKLMIAIAIFFTFTL-----------QFYVPVTILWKGLEHKIRPEKQNISE 477
            ..::... .:.|::.:||.:....|.|:           .|:||         .:..| |:.|..
Worm   312 IPSIQTV-WIQQAINIMITVHCILTLTIVFNPLMQEVEELFHVP---------QRFGP-KRAIVR 365

  Fly   478 YGLRVFLVLLCGGIAVALPNLGPFISLIGAVCLSTLGMIVPAT--IELAVYHE------DPGYGR 534
            .|:.|.:|.    :|.::|..||.:.|:|...|:...:|:|..  |.|..|..      .||.|.
Worm   366 TGIMVAVVF----VAESVPTFGPLLDLVGGSTLTLTSVIMPCLFYIYLNAYKRKEEITGKPGNGP 426

  Fly   535 FNWR--LWKNSG--------LILFGVVGFVAGTYVSIIE 563
            ..||  :..|..        :::.|::|....|:.:|:|
Worm   427 VGWRDVITFNQKPTLCICIIIMIIGLIGGGCATFSAIVE 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43693	NP_001261694.1	SdaC	153..561	CDD:223884	102/466 (22%)
CG43693	NP_001261694.1	SLC5-6-like_sbd	158..562	CDD:294310	100/456 (22%)
Y32F6A.4	NP_505680.2	SLC5-6-like_sbd	54..415	CDD:382020	90/403 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0814
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820