DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43693 and slc38a10

DIOPT Version :9

Sequence 1:	NP_001261694.1	Gene:	CG43693 / 39231	FlyBaseID:	FBgn0263776	Length:	572	Species:	Drosophila melanogaster
Sequence 2:	XP_004916417.2	Gene:	slc38a10 / 100488480	XenbaseID:	XB-GENE-958197	Length:	1066	Species:	Xenopus tropicalis

Alignment Length:	451	Identity:	94/451 - (20%)
Similarity:	171/451 - (37%)	Gaps:	124/451 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   167 VHLLKGSLGSGILAMPMAFSHAGLWFGLVATFAVGTLCTYCVH----ILVKCAHILCRRRKIPMM 227
            ::::...:|..:|.||..|...|:..|.:...    ||.:..|    .|||.|.:..||.
Frog    10 MNIVNSIVGVSVLTMPFCFKQCGIILGTLLLM----LCAWMTHQSCMFLVKSASVSKRRT----- 65

  Fly   228 GFADVAEQAFLDGPPALNRWSRFIRFMVNTFLVIDLLGCCCIYLVFV------------ATNVEQ 280
             :|.:          |.|.:.:..:.||.|.::..:||.|..:.|.:            ...|.:
Frog    66 -YAGL----------AFNAYGKAGKMMVETSMIGLMLGTCIAFYVVIGDLGSSFFARLLGLQVTE 119

  Fly   281 VVRVYMETELSIRVWIMIVTAPLIFMCLVRNLKFLTPFSMIANILMFVGIVITF--IYMFSDIPA 343
            ..||::...:|     :.:..||   .|.||        |:|:|..|..:.:.|  ::||..:.:
Frog   120 GFRVFLLFSVS-----LCIVLPL---SLQRN--------MMASIQSFSAMALMFYTVFMFVIVLS 168

  Fly   344 PVERPGI--------VSVTEWPLFFGTV-----IFALEGIGVVMSLENDMKNPSHFIGCPSVLNF 395
            ..:. |:        ||...|...|..:     .||.:  ..|:...:.:..||..| ..|:...
Frog   169 SFKH-GLFSGQWLKHVSYVRWEGVFRCIPIYGMSFACQ--SQVLPTYDSLDEPSVKI-MSSIFAL 229

  Fly   396 GMGLVIALYTLVGFFGFLKYGPETQASITLNLPLEDKLAQSVKL--MIAIAIFF----------- 447
            .:.:|...|..|||||::.:......::.:|.| .:.:.:.:::  |:::|:.|
Frog   230 SLNVVTTFYITVGFFGYVSFTESIAGNVLVNFP-SNLVTEMIRVGFMMSVAVGFPMMILPCRQAL 293

  Fly   448 ------------TFTLQFYVPVTILWKGLEHKIRPEKQNISEYGLRVFLVLLCGGIAVALPNLGP 500
                        |||...|:|      .|..|:         ..|.|....:.|||.:  ||:..
Frog   294 NTLLFEQQQKDGTFTAGGYMP------PLRFKV---------LTLVVVFGTMLGGILI--PNVET 341

  Fly   501 FISLIGAVCLSTLGMIVPATIELAVYHEDPGYGRFNWRLWKNSGLILFGVVGFVAGTYVSI 561
            .:.|.||...|.:.:|.||.|          |.:.:.:...:..::..|:|..|..||.::
Frog   342 ILGLTGATMGSLICLICPALI----------YKKIHKKGLTSQFILGVGLVILVISTYATL 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43693	NP_001261694.1	SdaC	153..561	CDD:223884	94/449 (21%)
CG43693	NP_001261694.1	SLC5-6-like_sbd	158..562	CDD:294310	94/451 (21%)
slc38a10	XP_004916417.2	SLC5-6-like_sbd	3..393	CDD:382020	94/451 (21%)
slc38a10	XP_004916417.2	PTZ00121	<396..1013	CDD:173412
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910