DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment klu and sqz

DIOPT Version :9

Sequence 1:	NP_001261690.1	Gene:	klu / 39228	FlyBaseID:	FBgn0013469	Length:	818	Species:	Drosophila melanogaster
Sequence 2:	NP_524403.1	Gene:	sqz / 42300	FlyBaseID:	FBgn0010768	Length:	535	Species:	Drosophila melanogaster

Alignment Length:	189	Identity:	61/189 - (32%)
Similarity:	85/189 - (44%)	Gaps:	33/189 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   527 MEMPLHP-------LHH--QQMHHSQVPTTTVGVPVIKGDVASPTTKETVAWRYNLDVSPVVEEM 582
            ||...||       |||  ||.|..|:..:      .....:.||..|....:|:.:.||..::|
  Fly    72 MEQQPHPDQQQQQHLHHPQQQQHPPQLKVS------YSAPNSPPTPHEQQEQKYDPNRSPPRQQM 130

  Fly   583 PPGSDVAYVCPTCGQMFSLHDRLAKHMASRHKSRNPANDIAKAYSCDVCRRSFARSDMLTRHMRL 647
            ...|...                :...:...:||....|.||.|.|..|.:|||.|..|::|.|:
  Fly   131 SSASGSG----------------SNGSSPEEESRRGDGDQAKPYKCGSCSKSFANSSYLSQHTRI 179

  Fly   648 HTGVKPYTCKVCGQVFSRSDHLSTHQRTHTGEKPYKCPQ--CPYAACRRDMITRHMRTH 704
            |.|:|||.|::|.:.|::..||..|.|||||:|||||..  ||.|..:...:..|.|.|
  Fly   180 HLGIKPYRCEICQRKFTQLSHLQQHIRTHTGDKPYKCRHAGCPKAFSQLSNLQSHSRCH 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
klu	NP_001261690.1	FYDLN_acid	<182..248	CDD:302856
		C2H2 Zn finger	592..613	CDD:275368	0/20 (0%)
		COG5048	607..>687	CDD:227381	36/81 (44%)
		zf-C2H2	626..648	CDD:278523	10/21 (48%)
		C2H2 Zn finger	628..648	CDD:275368	9/19 (47%)
		zf-H2C2_2	640..665	CDD:290200	11/24 (46%)
		C2H2 Zn finger	656..676	CDD:275368	7/19 (37%)
		zf-H2C2_2	668..690	CDD:290200	15/23 (65%)
		C2H2 Zn finger	684..704	CDD:275368	6/21 (29%)
sqz	NP_524403.1	C2H2 Zn finger	160..180	CDD:275368	9/19 (47%)
		zf-H2C2_2	172..197	CDD:290200	11/24 (46%)
		zf-C2H2	186..208	CDD:278523	8/21 (38%)
		C2H2 Zn finger	188..208	CDD:275368	7/19 (37%)
		zf-C2H2_8	191..271	CDD:292531	21/48 (44%)
		zf-H2C2_2	200..227	CDD:290200	16/26 (62%)
		C2H2 Zn finger	216..238	CDD:275368	6/21 (29%)
		C2H2 Zn finger	246..266	CDD:275368
		C2H2 Zn finger	277..297	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24381
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100