DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment klu and CG4318

DIOPT Version :9

Sequence 1:	NP_001261690.1	Gene:	klu / 39228	FlyBaseID:	FBgn0013469	Length:	818	Species:	Drosophila melanogaster
Sequence 2:	NP_572860.2	Gene:	CG4318 / 32266	FlyBaseID:	FBgn0030455	Length:	236	Species:	Drosophila melanogaster

Alignment Length:	212	Identity:	47/212 - (22%)
Similarity:	85/212 - (40%)	Gaps:	30/212 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   502 PNSPYANAMNAAHAAAAAAAAAMIKM------EMPLHPLHHQQMHHSQVPTTTVGVPVIKGDVAS 560
            |..|:...:..:.|..|..|..|..:      ||.:     .:|::.:..:....|.:|: .|..
  Fly    44 PKDPFPKTICQSCALDAQTAYGMDSVQVIEQDEMVV-----SEMNYEEEGSNDSDVELIE-PVDG 102

  Fly   561 PTTKETVAWRYNLDVSPVVEEMPPGSDVAYVCPTCGQMFSLHDRLAKHMASRHKSRNPANDIAKA 625
            ....||:    :|.:.      .||.:|..:||....  :.:..:::..|.:...:..   :.|.
  Fly   103 SQEMETI----DLTID------SPGDNVENMCPNSNS--NGNGNVSQSSAQKDTKKKM---LKKT 152

  Fly   626 YSCDVCRRSFARSDMLTRHMRLHTGVKPYTCKVCGQVFSRSDHLSTHQRTHTGE---KPYKCPQC 687
            :.|::|.:.|.....|..||.:|...|||.|..|.|.:::...|..|:|.|:..   :.|||.:|
  Fly   153 HKCNICGKYFMLPAHLKCHMWVHAREKPYKCLQCSQSYAQIRGLRRHERVHSSRPELRSYKCSRC 217

  Fly   688 PYAACRRDMITRHMRTH 704
            |....|...:..|...|
  Fly   218 PKIFNRNSALKNHETMH 234

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
klu	NP_001261690.1	FYDLN_acid	<182..248	CDD:302856
		C2H2 Zn finger	592..613	CDD:275368	3/20 (15%)
		COG5048	607..>687	CDD:227381	22/82 (27%)
		zf-C2H2	626..648	CDD:278523	6/21 (29%)
		C2H2 Zn finger	628..648	CDD:275368	6/19 (32%)
		zf-H2C2_2	640..665	CDD:290200	10/24 (42%)
		C2H2 Zn finger	656..676	CDD:275368	6/19 (32%)
		zf-H2C2_2	668..690	CDD:290200	9/24 (38%)
		C2H2 Zn finger	684..704	CDD:275368	5/19 (26%)
CG4318	NP_572860.2	zf-AD	5..>64	CDD:285071	4/19 (21%)
		C2H2 Zn finger	155..175	CDD:275368	6/19 (32%)
		zf-H2C2_2	167..192	CDD:290200	10/24 (42%)
		COG5048	<179..>236	CDD:227381	18/56 (32%)
		C2H2 Zn finger	183..203	CDD:275368	6/19 (32%)
		C2H2 Zn finger	214..234	CDD:275368	5/19 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469263
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930