DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment klu and Zbtb43

DIOPT Version :9

Sequence 1:	NP_001261690.1	Gene:	klu / 39228	FlyBaseID:	FBgn0013469	Length:	818	Species:	Drosophila melanogaster
Sequence 2:	NP_001012094.1	Gene:	Zbtb43 / 311872	RGDID:	1310287	Length:	503	Species:	Rattus norvegicus

Alignment Length:	421	Identity:	91/421 - (21%)
Similarity:	133/421 - (31%)	Gaps:	128/421 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   334 YPSPLQHTPSSIASETETS-------PNAQERKSSSNHVLPHALLANNSPPPSLPSPPRSESSVT 391
            :.||.....:.:|...|..       |.|||.:...|.        ..|....|      .|.||
  Rat   176 HQSPSSSNYNGLAESFELGSGGHTDFPKAQELRDGENE--------EESTKDEL------SSQVT 226

  Fly   392 NNVATTTTSSTTKKRSSPKPKGKKGEK----------------KPMPPPQERPLDLCMRNEVEPK 440
            .:....:.|||...|.|.:...:.||:                ||...|..|.:      .|:|:
  Rat   227 EHEYLPSNSSTEHDRLSTEMASQDGEEGTNDSTEFHYTRPLYSKPSIMPHRRWI------HVKPE 285

  Fly   441 KYKKSGSKSSLESRSAGMMPPPPALSAASSLESMSALSPASSSHSGHMPITSAATPNHQPPPNSP 505
            :         ||....||                       ..|        ||...||.   |.
  Rat   286 R---------LEQPWDGM-----------------------DVH--------AAYDEHQV---SE 307

  Fly   506 YANAMNAAHAAAAAAAAAMI-----KMEMPLHPLHHQQMHHSQVPTTTVGVPVIKGD-----VAS 560
            ..|.|...|:|..:.|....     |:|:..........:..||......:....|:     :..
  Rat   308 SVNTMQTDHSAQPSGAEEEFQIVEKKVEVEFDEHAEGSNYDEQVDFYGSSMEEFSGEKLGGGLIG 372

  Fly   561 PTTKETVAWRYNLDVSPVVEEMPPGSDVAYVCPTCGQMFSLHDRLAKHMASRHKSRNPANDIAKA 625
            ...:..:|..|:.::..|:......|.:.         ||..|:|
  Rat   373 HKQETALAAGYSENIEMVMGIKEEASHLG---------FSATDKL-------------------- 408

  Fly   626 YSCDVCRRSFARSDMLTRHMRLHTGVKPYTCKVCGQVFSRSDHLSTHQRTHTGEKPYKCPQCPYA 690
            |.|. |.:||.......|||.:|.|::||.|.|||:.|....||..|.:.|||.|||:|..|...
  Rat   409 YPCQ-CGKSFTHKSQRDRHMSMHLGLRPYGCSVCGKKFKMKHHLVGHMKIHTGIKPYECNICAKR 472

  Fly   691 ACRRDMITRHMRTHTRYDSRGGSREGREGRE 721
            ...||...||:.:.|:  |...::.|:...|
  Rat   473 FMWRDSFHRHVTSCTK--SYEAAKAGQNTTE 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
klu	NP_001261690.1	FYDLN_acid	<182..248	CDD:302856
		C2H2 Zn finger	592..613	CDD:275368	4/20 (20%)
		COG5048	607..>687	CDD:227381	27/79 (34%)
		zf-C2H2	626..648	CDD:278523	8/21 (38%)
		C2H2 Zn finger	628..648	CDD:275368	7/19 (37%)
		zf-H2C2_2	640..665	CDD:290200	12/24 (50%)
		C2H2 Zn finger	656..676	CDD:275368	8/19 (42%)
		zf-H2C2_2	668..690	CDD:290200	11/21 (52%)
		C2H2 Zn finger	684..704	CDD:275368	6/19 (32%)
Zbtb43	NP_001012094.1	BTB_POZ_ZBTB43	44..164	CDD:349536
		C2H2 Zn finger	412..430	CDD:275368	6/18 (33%)
		C2H2 Zn finger	438..458	CDD:275368	8/19 (42%)
		zf-H2C2_2	450..473	CDD:404364	11/22 (50%)
		C2H2 Zn finger	466..483	CDD:275368	5/16 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166344846
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930