DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Aps and nudt4b

DIOPT Version :9

Sequence 1:	NP_648421.1	Gene:	Aps / 39226	FlyBaseID:	FBgn0036111	Length:	177	Species:	Drosophila melanogaster
Sequence 2:	NP_001004648.1	Gene:	nudt4b / 447910	ZFINID:	ZDB-GENE-040912-79	Length:	178	Species:	Danio rerio

Alignment Length:	175	Identity:	98/175 - (56%)
Similarity:	128/175 - (73%)	Gaps:	3/175 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 VKEKPNSTRIYDKDGFRRRAACICVKSENEAEVLLVTSSRRPELWIVPGGGVEPEEESSVTAVRE 66
            :|.|||.||.||::||:|||||:|.|::.|.|||||:|||.|:.|||||||:|||||....||||
Zfish     1 MKFKPNQTRTYDREGFKRRAACLCFKNDREDEVLLVSSSRNPDQWIVPGGGMEPEEEPCGAAVRE 65

  Fly    67 VLEEAGVVGDLGRCLGVFE-NNDHMHRTEVFVMNVTQELDEWEDSRSIGRKRQWFTIDDALSQLA 130
            |.|||||.|.|||.||||| |.|..|||.|:|:.||:.||.||||.:|||||:||::|:|:..|.
Zfish    66 VYEEAGVKGKLGRLLGVFEQNQDRKHRTYVYVLTVTETLDAWEDSVNIGRKREWFSVDEAIRVLQ 130

  Fly   131 LHKPTQQHYLMQLQHSKTLD-NTNRVVNATHPPKLTNA-ATPAAS 173
            .|||....||.:|:.:::.. |.|.::..|:|..||.. :|||::
Zfish   131 GHKPVHAEYLRRLRINRSSSTNGNLLLPQTNPSNLTPLFSTPASA 175

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Aps	NP_648421.1	Nudix_Hydrolase_9	19..137	CDD:240024	76/118 (64%)
nudt4b	NP_001004648.1	Nudix_Hydrolase_9	18..127	CDD:240024	72/108 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593311
Domainoid	1	1.000	156	1.000	Domainoid score	I4138
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	193	1.000	Inparanoid score	I3833
OMA	1	1.010	-	-		QHG58445
OrthoDB	1	1.010	-	-		D1324716at2759
OrthoFinder	1	1.000	-	-		FOG0000621
OrthoInspector	1	1.000	-	-		otm24589
orthoMCL	1	0.900	-	-		OOG6_101097
Panther	1	1.100	-	-	O	PTHR12629
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R74
SonicParanoid	1	1.000	-	-		X795
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.940