DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Aps and nudt4a

DIOPT Version :9

Sequence 1:	NP_648421.1	Gene:	Aps / 39226	FlyBaseID:	FBgn0036111	Length:	177	Species:	Drosophila melanogaster
Sequence 2:	NP_001296990.1	Gene:	nudt4a / 378990	ZFINID:	ZDB-GENE-031010-33	Length:	226	Species:	Danio rerio

Alignment Length:	179	Identity:	96/179 - (53%)
Similarity:	118/179 - (65%)	Gaps:	14/179 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVKEKPNSTRIYDKDGFRRRAACICVKSENEAEVLLVTSSRRPELWIVPGGGVEPEEESSVTAVR 65
            |:|.|||.||.||.:||::||||:|.|::.|.|||||:|||.|:.|||||||:|||||....|||
Zfish    44 MMKFKPNQTRTYDGEGFKKRAACLCFKNDREDEVLLVSSSRHPDQWIVPGGGMEPEEEPGGAAVR 108

  Fly    66 EVLEEAGVVGDLGRCLGVFE-NNDHMHRTEVFVMNVTQELDEWEDSRSIGRKRQWFTIDDALSQL 129
            ||.|||||.|.|||.||||| |.|..|||.|:|:.||:.|::||||.:|||||:||.||:|:..|
Zfish   109 EVYEEAGVRGTLGRLLGVFEQNQDSKHRTYVYVLTVTETLEDWEDSVNIGRKRKWFKIDEAIRVL 173

  Fly   130 ALHKPTQQHYLMQL-------------QHSKTLDNTNRVVNATHPPKLT 165
            ..|||....||.:|             ....|.||.:....|:|...||
Zfish   174 QCHKPFHAEYLRKLTPRCGPTNGNTQEPTMNTDDNASLRQTASHDCGLT 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Aps	NP_648421.1	Nudix_Hydrolase_9	19..137	CDD:240024	75/118 (64%)
nudt4a	NP_001296990.1	Nudix_Hydrolase_9	62..178	CDD:240024	73/115 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593312
Domainoid	1	1.000	156	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0494
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	193	1.000	Inparanoid score	I3833
OMA	1	1.010	-	-		QHG58445
OrthoDB	1	1.010	-	-		D1324716at2759
OrthoFinder	1	1.000	-	-		FOG0000621
OrthoInspector	1	1.000	-	-		otm24589
orthoMCL	1	0.900	-	-		OOG6_101097
Panther	1	1.100	-	-	O	PTHR12629
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R74
SonicParanoid	1	1.000	-	-		X795
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800