DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Aps and NUDT7

DIOPT Version :9

Sequence 1:	NP_648421.1	Gene:	Aps / 39226	FlyBaseID:	FBgn0036111	Length:	177	Species:	Drosophila melanogaster
Sequence 2:	NP_001099133.1	Gene:	NUDT7 / 283927	HGNCID:	8054	Length:	238	Species:	Homo sapiens

Alignment Length:	162	Identity:	39/162 - (24%)
Similarity:	54/162 - (33%)	Gaps:	54/162 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 VKSENEAEVLLVTSS----RRPELWIVPGGGVEPEE-ESSVTAVREVLEEAG-------VVGDLG 78
            |..|.:..:|....|    |.|.....|||..:|.: :.:.||:||..||.|       ||..|.
Human    47 VAKEGKLHLLFTVRSEKLRRAPGEVCFPGGKRDPTDMDDAATALREAQEEVGLRPHQVEVVCCLV 111

  Fly    79 RCL-----------GVFENNDHMHRTEVFVMNVTQELDEWEDSRSIGRKRQWFTIDDALSQLA-- 130
            .||           |:.::|.........|.:|                        .|..||
Human   112 PCLIDTDTLITPFVGLIDHNFQAQPNPAEVKDV------------------------FLVPLAYF 152

  Fly   131 LHKPT-QQHYLMQLQHSKTLDNTNRVVNATHP 161
            ||... .|||:.:|.|.    ..|.:...|:|
Human   153 LHPQVHDQHYVTRLGHR----FINHIFEYTNP 180

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Aps	NP_648421.1	Nudix_Hydrolase_9	19..137	CDD:240024	31/136 (23%)
NUDT7	NP_001099133.1	CoAse	41..201	CDD:239518	39/162 (24%)
		Nudix box	77..98		7/20 (35%)
		Microbody targeting signal. /evidence=ECO:0000250	236..238
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0494
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900