DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment OXA1L and OXA1

DIOPT Version :9

Sequence 1:	NP_648417.1	Gene:	OXA1L / 39222	FlyBaseID:	FBgn0027615	Length:	441	Species:	Drosophila melanogaster
Sequence 2:	NP_011081.1	Gene:	OXA1 / 856898	SGDID:	S000000956	Length:	402	Species:	Saccharomyces cerevisiae

Alignment Length:	380	Identity:	111/380 - (29%)
Similarity:	173/380 - (45%)	Gaps:	52/380 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 RITRGSSLPLAAPE-KWSNLGQLRFASGGATAAGVSATKGEEFMQAVPKTELVDLPDIPAAPVPP 104
            |:....::.|..|. .|.:....||.|.|..|..||..:             ..||.|.......
Yeast    18 RLATARTIVLPRPHPSWISFQAKRFNSTGPNANDVSEIQ-------------TQLPSIDELTSSA 69

  Fly   105 PADGLNVMDVM----NAAGEPS-----FASIGLGG---WSPVGMVQNCLEFLHCTWDIPWWGTIA 157
            |:...:..|::    ...||.|     ..||||..   | |..::|:.||.:|....:|||||||
Yeast    70 PSLSASTSDLIANTTQTVGELSSHIGYLNSIGLAQTWYW-PSDIIQHVLEAVHVYSGLPWWGTIA 133

  Fly   158 IGTLAVRTIIFPLVILAQRNSAKMNNNMPQMQMLQLKM--TEARQSGNAIESARYAQEMMLFMRE 220
            ..|:.:|.::|||.:.:....|:.::..|::..|..|:  |...|.|..:     |.:....:..
Yeast   134 ATTILIRCLMFPLYVKSSDTVARNSHIKPELDALNNKLMSTTDLQQGQLV-----AMQRKKLLSS 193

  Fly   221 KGVNPLKN--MVVPLAQAPLFISFFMGLRQMANAPVESMRDGGLFWFTDLTMADPFYLLPLITSA 283
            .|:   ||  :..|:.|.|:.:.||..||.|||.||:...:.|:.||||||.|||:..|.:||:|
Yeast   194 HGI---KNRWLAAPMLQIPIALGFFNALRHMANYPVDGFANQGVAWFTDLTQADPYLGLQVITAA 255

  Fly   284 TLYLTIEIG--TDSARLSAANMNTMKYVLRALPIVIFPFTMNFPAAILTYWACSNFISLGQVAVL 346
            .......:|  |.:.:.|    :.||.:...|||:..|.|||..:|::.|:|.:...|:.|..:|
Yeast   256 VFISFTRLGGETGAQQFS----SPMKRLFTILPIISIPATMNLSSAVVLYFAFNGAFSVLQTMIL 316

  Fly   347 RIPSVREYFKI---EKMLTHAPSALPPKK-GFVGGMKESWDNMKISKEIEERQRL 397
            |...||...||   .|..|....|.|.:. |....:|.   |::.:::..||::|
Yeast   317 RNKWVRSKLKITEVAKPRTPIAGASPTENMGIFQSLKH---NIQKARDQAERRQL 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
OXA1L	NP_648417.1	yidC_oxa1_cterm	152..342	CDD:274665	64/195 (33%)
OXA1	NP_011081.1	5TM_Oxa1-like	125..319	CDD:410993	68/205 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343823
Domainoid	1	1.000	99	1.000	Domainoid score	I1598
eggNOG	1	0.900	-	-		E1_COG0706
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H31281
Inparanoid	1	1.050	129	1.000	Inparanoid score	I1259
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001122
OrthoInspector	1	1.000	-	-		oto99971
orthoMCL	1	0.900	-	-		OOG6_100866
Panther	1	1.100	-	-	LDO	PTHR12428
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R242
SonicParanoid	1	1.000	-	-		X1877
TreeFam	1	0.960	-	-
	14	13.780