DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment OXA1L and Oxa1l

DIOPT Version :9

Sequence 1:	NP_648417.1	Gene:	OXA1L / 39222	FlyBaseID:	FBgn0027615	Length:	441	Species:	Drosophila melanogaster
Sequence 2:	NP_001162055.1	Gene:	Oxa1l / 691393	RGDID:	1585024	Length:	433	Species:	Rattus norvegicus

Alignment Length:	426	Identity:	154/426 - (36%)
Similarity:	242/426 - (56%)	Gaps:	40/426 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LAHRMQLWRTTNAAMAMTSAAGRFTPQAS------TGSRRDLYLQRITRGSSLPLAAPEKWSNLG 60
            :..|.||.|......:..|.||...|.|:      :||.|..|       :.|.:..|...|
  Rat     6 VCRRWQLLRLLQPPRSFHSVAGSLKPLATKLLAARSGSGRPHY-------ALLAVLTPRCIS--- 60

  Fly    61 QLRFASGGATAAGVSATKGEEFMQAVPKTELVDLPDIPAAPVP---PPADGLNVMDVMNAAGEPS 122
                     |:|.:.|    |....||       |.:|||..|   |........||:..|.|.|
  Rat    61 ---------TSAALFA----EAQVQVP-------PVVPAASAPAAVPEVASAGPADVVQCATEQS 105

  Fly   123 FASIGLGGWSPVGMVQNCLEFLHCTWDIPWWGTIAIGTLAVRTIIFPLVILAQRNSAKMNNNMPQ 187
            ||.:|||.::|||::||.||::|....:||||.||..|:..|.::|||::..||.:||::|:||:
  Rat   106 FAELGLGSYTPVGLIQNLLEYIHVDLGLPWWGAIATCTVLARCLVFPLIVKGQREAAKIHNHMPE 170

  Fly   188 MQMLQLKMTEARQSGNAIESARYAQEMMLFMREKGVNPLKNMVVPLAQAPLFISFFMGLRQMANA 252
            ||....::.||:.||:..|..:...||..:.::..:...:.:::||.|||:|||||:.||:|||.
  Rat   171 MQKFSARIREAKLSGDQAEFYKATIEMTHYQKKHDIKFFRPLILPLTQAPIFISFFIALREMANL 235

  Fly   253 PVESMRDGGLFWFTDLTMADPFYLLPLITSATLYLTIEIGTDSARLSAANMNTMKYVLRALPIVI 317
            ||.|::.|||:||.|||::||.|:|||:.:||::..:|:|.::. :.::::..|:.|:|.:|:.:
  Rat   236 PVPSLQTGGLWWFQDLTVSDPIYVLPLVVTATMWGVLELGAETG-MQSSDLQLMRNVIRVMPLAV 299

  Fly   318 FPFTMNFPAAILTYWACSNFISLGQVAVLRIPSVREYFKIEKMLTHAPSALPPKKGFVGGMKESW 382
            .|.|::||:|:..||..||..||.|||.||.|:||...||.:.:.|.||.|||::||:...|:.|
  Rat   300 LPVTIHFPSAVFMYWLSSNVFSLCQVACLRFPAVRTALKIPQRVVHDPSKLPPREGFLKSFKKGW 364

  Fly   383 DNMKISKEIEERQRLDEIRFAKAGKGPLVKTYKFDP 418
            .|.:|:..:.||:...:.....|.:|||.:|:..:|
  Rat   365 KNAEIAHRLREREERMQKHLDLAARGPLRQTFTHNP 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
OXA1L	NP_648417.1	yidC_oxa1_cterm	152..342	CDD:274665	77/189 (41%)
Oxa1l	NP_001162055.1	5TM_Oxa1-like	132..331	CDD:410993	83/199 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340866
Domainoid	1	1.000	175	1.000	Domainoid score	I3566
eggNOG	1	0.900	-	-		E1_COG0706
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H31281
Inparanoid	1	1.050	286	1.000	Inparanoid score	I2761
OMA	1	1.010	-	-		QHG48060
OrthoDB	1	1.010	-	-		D1314061at2759
OrthoFinder	1	1.000	-	-		FOG0001122
OrthoInspector	1	1.000	-	-		oto97902
orthoMCL	1	0.900	-	-		OOG6_100866
Panther	1	1.100	-	-	LDO	PTHR12428
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1877
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770