DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment OXA1L and oxa1l

DIOPT Version :9

Sequence 1:	NP_648417.1	Gene:	OXA1L / 39222	FlyBaseID:	FBgn0027615	Length:	441	Species:	Drosophila melanogaster
Sequence 2:	NP_001098600.2	Gene:	oxa1l / 562963	ZFINID:	ZDB-GENE-071004-49	Length:	469	Species:	Danio rerio

Alignment Length:	446	Identity:	170/446 - (38%)
Similarity:	254/446 - (56%)	Gaps:	40/446 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 TPQAST----GSRRDLYLQR----ITRGSSLPLAAPEKWSNLGQLRFASGGATAAGV---SATKG 79
            ||..||    .:|.:.::||    ..:|:...:.|.....|.||....:    |.|:   |:...
Zfish    23 TPSVSTLPIVLTRNEWFVQRSHLHTGKGNRGLVRALLGCQNHGQFLLVN----AVGIRHNSSQTV 83

  Fly    80 EEFMQAV-----PKTELVDLP-DIPAAPVPPPAD------------GLNVMDVMNAAG-EPSFAS 125
            |..:|.|     |....:..| .|||..|.|...            .|..:||:...| |.|.:.
Zfish    84 ETTVQRVSTPSEPPDAAISAPASIPAPAVDPTPSVTPQITEQVAEAPLTALDVLQGVGAEASLSE 148

  Fly   126 IGLGGWSPVGMVQNCLEFLHCTWDIPWWGTIAIGTLAVRTIIFPLVILAQRNSAKMNNNMPQMQM 190
            :||...:|||::||.|||:|.:..:||||.|..||:..|..:||:::..||.:||:||.||:|..
Zfish   149 LGLCNSTPVGLIQNLLEFMHVSIGLPWWGAIVAGTIVARCAVFPVIVKGQREAAKLNNVMPEMTK 213

  Fly   191 LQLKMTEARQSGNAIESARYAQEMMLFMREKGVNPLKNMVVPLAQAPLFISFFMGLRQMANAPVE 255
            |..:|.||:||||..|.::...::|:|.::|.|||.:..:|||.|||:|:|||:.||:|:..||.
Zfish   214 LTNRMNEAKQSGNKFEFSKAYTDLMMFQKKKDVNPFRGFLVPLVQAPIFLSFFIALRKMSELPVP 278

  Fly   256 SMRDGGLFWFTDLTMADPFYLLPLITSATLYLTIEIGTDSARLSAANMNTMKYVLRALPIVIFPF 320
            |::.|||:||||||.|||||:||:..:.|:...:|:|.:|. :...|:..||.|.|.:|.||.|.
Zfish   279 SLQTGGLWWFTDLTAADPFYILPIAVTGTMVAILELGAESG-VDNPNLRAMKTVFRIMPFVILPL 342

  Fly   321 TMNFPAAILTYWACSNFISLGQVAVLRIPSVREYFKIEKMLTHAPSALPPKKGFVGGMKESWDNM 385
            |:|||.|:.|||..||..||.||||||.|:||:..:|.:.:.|..||||..:||...:|:.|.|.
Zfish   343 TINFPTAVFTYWMTSNLFSLAQVAVLRHPAVRQKLRIPERIVHPQSALPENEGFFATVKKGWKNA 407

  Fly   386 KISKEIEERQRLDEIRFAKAGKGPLVKTYKFDP-TKVAKPIS----AEPHMRLKEP 436
            ::::::|||:|..:.....|.||||.:|:..:| .:.|.|:|    :.|:...|.|
Zfish   408 QLAQQLEERERRIKGHLDIAAKGPLRQTFTHNPLQQSAAPMSTGKPSNPNQGKKRP 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
OXA1L	NP_648417.1	yidC_oxa1_cterm	152..342	CDD:274665	90/189 (48%)
oxa1l	NP_001098600.2	YidC	122..383	CDD:223778	118/261 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580719
Domainoid	1	1.000	203	1.000	Domainoid score	I2934
eggNOG	1	0.900	-	-		E1_COG0706
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H31281
Inparanoid	1	1.050	299	1.000	Inparanoid score	I2675
OMA	1	1.010	-	-		QHG48060
OrthoDB	1	1.010	-	-		D1314061at2759
OrthoFinder	1	1.000	-	-		FOG0001122
OrthoInspector	1	1.000	-	-		oto40096
orthoMCL	1	0.900	-	-		OOG6_100866
Panther	1	1.100	-	-	LDO	PTHR12428
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R242
SonicParanoid	1	1.000	-	-		X1877
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800