Protein Alignment CG6418 and Ddx5

DIOPT Version :10

• Sequence 1: NP_648413.1
• Gene: CG6418 / 39218
• FlyBaseID: FBgn0036104
• Length: 791
• Species: Drosophila melanogaster
• Sequence 2: NP_031866.2
• Gene: Ddx5 / 13207
• MGIID: 105037
• Length: 615
• Species: Mus musculus
• Alignment Length: 649
• Identity: 219/649 - (33%)
• Similarity: 324/649 - (49%)
• Gaps: 118/649 - (18%)

  Fly   188 RDEGSDQ-------------EIEYDEDGNP--IAPPKKKDIDPLPPIYHSEIEYEPFEKNFYTQH 237
            ||.|.|:             .:...:.|||  ....||.::|.||          .||||||.:|
Mouse     8 RDRGRDRGFGAPRFGGSRTGPLSGKKFGNPGEKLVKKKWNLDELP----------KFEKNFYQEH 62

  Fly   238 DDIAALDDEQVRELRRTLGVKVTGPSPPKPVTSFGHFGFDEQLIKAVRKAEYTQPTPIQAQAVPT 302
            .|:|....::|...||:..:.|.|.:.||||.:|....|...::..:.:..:|:||.||||..|.
Mouse    63 PDLARRTAQEVDTYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPV 127

  Fly   303 ALSGRDIIGIAKTGSGKTAAFIWPMLMHVMDQKQLKPGDGPIGLILAPTRELSLQIYNEAKKFGK 367
            ||||.|::|:|:||||||.:::.|.::|:..|..|:.|||||.|:|||||||:.|:...|.::.:
Mouse   128 ALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQQVQQVAAEYCR 192

  Fly   368 VYNLNVVCCYGGGSKWEQSKALEQGAEIIVATPGRMIDMVKMKATNLRRVTFLVLDEADRMFHMG 432
            ...|...|.|||..|..|.:.||:|.||.:|||||:||.::...|||||.|:|||||||||..||
Mouse   193 ACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMG 257

  Fly   433 FEPQVRSICNHVRPDRQCLMFSATFKKRIERLARDVLSDPVRIVQGDLN-EANQDITQSVYVFPN 496
            ||||:|.|.:.:|||||.||:|||:.|.:.:||.|.|.|.:.|..|.|. .||.:|.|.|.|
Mouse   258 FEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDV--- 319

  Fly   497 PLQKWNWLLCH-------LVKFL------SEGSVLIFVTKKVDAETVSNNLLIKEYNCLLLHGDM 548
                     ||       |::.:      .|...::||..|...:.::..:....:..:.:|||.
Mouse   320 ---------CHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDK 375

  Fly   549 DQADRNKVITQFKRKECDILVATDVAARGLDIPHIRNVVNYDTARDIETHTHRIGRTGRAGEKGN 613
            .|.:|:.|:.:||..:..||:|||||:||||:..::.|:|||.....|.:.||||||.|:.:.|.
Mouse   376 SQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGT 440

  Fly   614 AYTLVTDKDKEFAGHLVRNLEGADQLVPDDLMEL-------------AMKSSWFRSSRFKQGKGK 665
            |||..|..:.:....|:..|..|:|.:...|::|             .||..  |..|:..|| :
Mouse   441 AYTFFTPNNIKQVSDLISVLREANQAINPKLLQLVEDRGSGRSRGRGGMKDD--RRDRYSAGK-R 502

  Fly   666 RPTNTHTGLGYREKGNGGGGYGSA-----GGSESTASVSAHSPSDGPSSKAFSSSGPATDRYTAM 725
            ...||     :|::.|...||.:.     |........||.:.::|.....|.|:|        :
Mouse   503 GGFNT-----FRDRENYDRGYSNLLKRDFGAKTQNGVYSAANYTNGSFGSNFVSAG--------I 554

  Fly   726 REAFRS-----QYNNQFRASSDRTWEKTLPESGVFAAPMAPPSSSTQ--GASASSANNSSNQDA 782
            :.:||:     .|.|.:                          .|||  |::.::.:|..||.|
Mouse   555 QTSFRTGNPTGTYQNGY--------------------------DSTQQYGSNVANMHNGMNQQA 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6418	NP_648413.1	SrmB	269..634	CDD:440279	153/378 (40%)
Ddx5	NP_031866.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..39		7/30 (23%)
		DEAD-like_helicase_N	6..507	CDD:475120	194/523 (37%)
		Q motif	94..122		6/27 (22%)
		DEAD box	248..251		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	477..504		6/29 (21%)
		P68HR	498..532	CDD:429808	9/39 (23%)
		P68HR	551..583	CDD:429808	10/65 (15%)