DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment tna and AT1G08910

DIOPT Version :9

Sequence 1:	NP_001368945.1	Gene:	tna / 39217	FlyBaseID:	FBgn0026160	Length:	1186	Species:	Drosophila melanogaster
Sequence 2:	NP_172366.3	Gene:	AT1G08910 / 837412	AraportID:	AT1G08910	Length:	829	Species:	Arabidopsis thaliana

Alignment Length:	623	Identity:	133/623 - (21%)
Similarity:	214/623 - (34%)	Gaps:	207/623 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   608 SEEMRLTFP-VRDGIILAPFRLLHNLSVSNHVFHL--------KQNVYNTLMCRNDLELQLKCFH 663
            |:.:...:| |:.|.||..|.......:....||:        ||.|...::...|:.......|
plant   121 SQVIERFYPCVKLGHILVSFEAKPESKMMMKDFHISKKMPHSPKQKVGLFVVRTEDISRSNCIVH 185

  Fly   664 QDDRQMNTNWPHTVTVSANATPLN--IERSEKNSTALRPLYLKAVCQPGRNTLQLTASSCC-CSH 725
                      |..|:...|...::  :..|.::...| |..:.|:...|.|.||  |..|. .|:
plant   186 ----------PQGVSFLLNGKGIDKRVNISMESGPQL-PTNVTALLNLGANLLQ--AIGCFGGSY 237

  Fly   726 LFVLQLVHRPSVRQVLQTLHKRNLLPLEHSVQKIKRNLSQPEANAGPDATPQQQQQQGGGQQC-- 788
            |..:..:               :::||.:  :.:.::...||.             .|....|
plant   238 LIAIAFM---------------DVIPLPN--KPLLKDYVHPEV-------------VGSNSDCDI 272

  Fly   789 ----AKISLKCPITKSRIRLPARGHECKHVQCFDLEAYLMINSER--GSWRCPECSKSAITDTLE 847
                ::|||.|||:::||:||.:||.|||:||||...|:.:|:.|  |:.|
plant   273 IEGPSRISLSCPISRTRIKLPVKGHVCKHLQCFDFWNYVNMNTRRHHGAAR-------------- 323

  Fly   848 IDQYIWAILNTLGNSDVDEVIIDSSANWRA-------------LQHNGGMPNA------------ 887
                  .||..:|.:..| |:|.:...|..             ..|:.|.||:
plant   324 ------IILEEVGRNAAD-VVISADGTWMVETENDEDVELVPETTHDHGDPNSFINLGPTVKNPA 381

  Fly   888 ----------------PPPSNV--PSNPSGGSGS-----NSGNGSVNPTLPVIKQEL-------C 922
                            |..|.:  |||.:....|     |..:.|.| |||.:.:.|       .
plant   382 RDENEMETSTQVEEHNPCLSEIQGPSNDTHRPASDYTMLNQSHTSTN-TLPQLPRTLNAFDGQQF 445

  Fly   923 DDIAKVM----SPGSTQLPTWDSAQAMSPYNMHDMNSIASGNMMGNGGNTNQHGNRSSYDGFSGN 983
            .::.:|:    ||.|..||...| ...||.::...|:...|        |:....:||.  |.|:
plant   446 VNLPQVINTRDSPASQALPMTFS-PTPSPQDILATNAANFG--------TSMPAAQSSQ--FQGS 499

  Fly   984 HSDGSGGLPGGDGGVNSLDQLNAMEKSLSDQMPHTP----H---------------TPGAASHPM 1029
            |....|...|....:  :.:.|.:...:..|.|..|    |               .|...:||.
plant   500 HVTSLGNCEGRTSDL--MARWNHIYGRVQTQFPPAPLSHHHYSMQNQSPSPAQQRPVPSYIAHPQ 562

  Fly  1030 T-----------PGGPPSVSSSHNEPIS-GGTPN--------ANGSGSATNGSGNNNSSTGHNSP 1074
            |           ...|.|::.....|:: ||..|        |:......|..||    |.|.|
plant   563 TFHVNYGENADQRWMPSSIAHPQTLPVNYGGNTNQRPIPSSIAHPQTLPVNYRGN----TDHRS- 622

  Fly  1075 QTPGTPSRMGGGMGGSGSADSQQQQQEQLLNSLMSSQT 1112
             ||.:.:.:...:...|:||     |..:.:|:.:.||
plant   623 -TPYSITHLQTLLNYGGNAD-----QRPMPSSITNLQT 654

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tna	NP_001368945.1	Med15	216..>604	CDD:312941
tna	NP_001368945.1	SP-RING_ZMIZ	792..839	CDD:319705	23/48 (48%)
AT1G08910	NP_172366.3	RING	279..>317	CDD:302633	21/37 (57%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	74	1.000	Domainoid score	I3229
eggNOG	1	0.900	-	-		E1_KOG2169
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3494
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10782
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.000