Protein Alignment tna and Su(var)2-10

DIOPT Version :9

• Sequence 1: NP_001368945.1
• Gene: tna / 39217
• FlyBaseID: FBgn0026160
• Length: 1186
• Species: Drosophila melanogaster
• Sequence 2: NP_724749.1
• Gene: Su(var)2-10 / 35927
• FlyBaseID: FBgn0003612
• Length: 640
• Species: Drosophila melanogaster
• Alignment Length: 669
• Identity: 143/669 - (21%)
• Similarity: 221/669 - (33%)
• Gaps: 228/669 - (34%)

  Fly   536 GSGQSAGMQQAGGMCPAGPGAVATTGNPYQNQGFQQNYQHSPVPGNPTPPLTPACSVPYVSPNPD 600
            ||||  |:|..||......||      |:.       :.||.   |...|:           :||
  Fly   136 GSGQ--GVQVPGGQMNVVGGA------PFL-------HTHSI---NSQLPI-----------HPD 171

  Fly   601 IKPPMDNSEEMRLTFPVRDGIILAPFRLL--HNLSVSNHVFHL------------KQNVYNTLMC 651
            ::       ..:|.|....|.::.|..|:  :...|....|:.            .:::.|:...
  Fly   172 VR-------LKKLAFYDVLGTLIKPSTLVPRNTQRVQEVPFYFTLTPQQATEIASNRDIRNSSKV 229

  Fly   652 RNDLELQLK-CFHQDDRQMNTNWPHTVTVSAN----------------------ATPLNIERSEK 693
            .:.:::||: |..:........:|..|.|..|                      ..|:|:..:.|
  Fly   230 EHAIQVQLRFCLVETSCDQEDCFPPNVNVKVNNKLCQLPNVIPTNRPNVEPKRPPRPVNVTSNVK 294

  Fly   694 NSTALRPLYLKAVCQPGRNTLQLTASSC---CCSHLFVLQLVHRPSVRQVLQTLHKRNLLPLEHS 755
            .|..:              |..:|...|   ..|:...:.||.:.:..|:||.:..:.:.|.:::
  Fly   295 LSPTV--------------TNTITVQWCPDYTRSYCLAVYLVKKLTSTQLLQRMKTKGVKPADYT 345

  Fly   756 VQKIKRNLSQPEANAGPDATPQQQQQQGGGQQCAKISLKCPITKSRIRLPARGHECKHVQCFDLE 820
            ...||..|:: :|:.....|            ..|:||.||:.|.::.||.|...|.|:||||..
  Fly   346 RGLIKEKLTE-DADCEIATT------------MLKVSLNCPLGKMKMLLPCRASTCSHLQCFDAS 397

  Fly   821 AYLMINSERGSWRCPECSKSAITDTLEIDQYIWAIL-NTLGNSDVDEVIIDSSANWRALQHNGGM 884
            .||.:|..:.:|.||.|.|.||.|.|.||.|...:| ::|..||..|:.:....:|    ...|:
  Fly   398 LYLQMNERKPTWNCPVCDKPAIYDNLVIDGYFQEVLGSSLLKSDDTEIQLHQDGSW----STPGL 458

  Fly   885 PNAPPPSNVPSNPSGGSGSNSGNGSVNPTLPVIKQ--ELCDDIAKV----MSPGSTQLPTWDSAQ 943
            .:.....:.||.|:             ..:.||..  ||..|.||.    :||...:.||..|..
  Fly   459 RSETQILDTPSKPA-------------QKVEVISDDIELISDDAKPVKRDLSPAQDEQPTSTSNS 510

  Fly   944 AMSPYNMHDMNSIASGNMMGNGGNTNQHGNRSSYDGFSGNHSDGSGGLPGGDGGVNSLDQLNAME 1008
            ......:.|                                ||
  Fly   511 ETVDLTLSD--------------------------------SD---------------------- 521

  Fly  1009 KSLSDQMPHTPHTPGAASHPMTPGGPPSVSSSHNEPISGGTPNANGSGSATNGSGNNNSSTGHNS 1073
                |.||.....|.|..         :|:||          .:||||      |...:.|....
  Fly   522 ----DDMPLAKRRPPAKQ---------AVASS----------TSNGSG------GGQRAYTPAQQ 557

  Fly  1074 PQTPGTPSRMGGGMGGSGSADSQQQQQEQ-------------LLNSLMSSQTQLK-FSESDLSAE 1124
            ||...:|.:............|:||.|:|             ||.||.::....| |...||:|
  Fly   558 PQQSESPEQQASRQSPEKQTVSEQQLQQQQHEQPATAAVHASLLESLAAAVADQKHFQLLDLAA- 621

  Fly  1125 LQSFDAAAAAINDTAHDLN 1143
               ..|||||...:....|
  Fly   622 ---VAAAAAATASSGQSQN 637

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tna	NP_001368945.1	Med15	216..>604	CDD:312941	17/67 (25%)
		SP-RING_ZMIZ	792..839	CDD:319705	21/46 (46%)
Su(var)2-10	NP_724749.1	SAP	49..83	CDD:128789
		PINIT	171..307	CDD:291022	22/156 (14%)
		zf-MIZ	368..417	CDD:280964	21/48 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449144
Domainoid	1	1.000	66	1.000	Domainoid score	I2790
eggNOG	1	0.900	-	-		E1_KOG2169
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10782
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3884
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.870