Protein Alignment tna and Pias1

DIOPT Version :9

• Sequence 1: NP_001368945.1
• Gene: tna / 39217
• FlyBaseID: FBgn0026160
• Length: 1186
• Species: Drosophila melanogaster
• Sequence 2: NP_001100299.3
• Gene: Pias1 / 300772
• RGDID: 1307843
• Length: 651
• Species: Rattus norvegicus
• Alignment Length: 672
• Identity: 144/672 - (21%)
• Similarity: 207/672 - (30%)
• Gaps: 261/672 - (38%)

  Fly   572 NYQHSPVPGNPTP---------------PLTPA--------CSVPYVSP-----NPD-------- 600
            |...||:|...:|               ||.|.        ..:|:::.     :||
  Rat    79 NVHSSPMPATLSPSTIPQLTYDGHPASSPLLPVSLLGPKHELELPHLTSALHPVHPDIKLQKLPF 143

  Fly   601 -------IKP---PMDNSEEMRLT-FPVRDGIILAPFRLLHNLSVSNHVFHLKQNVYNTLMCRND 654
                   |||   ..|||:..|.| |    ...|.| :.:..:|.|..:...|        |...
  Rat   144 YDLLDELIKPTSLASDNSQRFRETCF----AFALTP-QQVQQISSSMDISGTK--------CDFT 195

  Fly   655 LELQLK-CFHQDDRQMNTNWPHTVTVSANATPLNIERSEKNSTALRPLYL---KAVCQPGR---- 711
            :::||: |..:.......::|..:.|..|..|.::           |.||   |...:|.|
  Rat   196 VQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSL-----------PGYLPPTKNGVEPKRPSRP 249

  Fly   712 -NTLQLTASSCCCSHLFVLQ--------------LVHRPSVRQVLQTLHKRNLLPLEHSVQKIKR 761
             |...|...|....:..|:.              ||.:.|...:||.|..:.:...:||...||.
  Rat   250 INITSLVRLSTTVPNTIVVSWTAEIGRTYSMAVYLVKQLSSTVLLQRLRAKGIRNPDHSRALIKE 314

  Fly   762 NLSQPEANAGPD---ATPQQQQQQGGGQQCAKISLKCPITKSRIRLPARGHECKHVQCFDLEAYL 823
            .|:     |.||   ||..           .::||.||:.|.|:.:|.|...|.|:||||...|:
  Rat   315 KLT-----ADPDSEIATTS-----------LRVSLLCPLGKMRLTIPCRALTCSHLQCFDATLYI 363

  Fly   824 MINSERGSWRCPECSKSAITDTLEIDQYIWAILNTLGNSDVDEVIIDSSANW------------- 875
            .:|.::.:|.||.|.|.|..:.|.||.....||...  :|.||:......:|
  Rat   364 QMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYC--TDCDEIQFKEDGSWAPMRSKKEVQEVT 426

  Fly   876 -----------RALQHNGGMPN-------------------------APP-----PSNVPSNPSG 899
                       ..|:|.....|                         .||     ||..|::|..
  Rat   427 ASYNGVDGCLSSTLEHQVASHNQSSNKNKKVEVIDLTIDSSSDEEEEEPPAKRTCPSLSPTSPLS 491

  Fly   900 GSG-----SNSGNGSVNPTLPV-----IKQELCDDIAKV--MSPGSTQLPTWDSAQAMSPYNMH- 951
            ..|     ..:...|..|:||.     |...|..|....  |:|              .||::.
  Rat   492 NKGILSLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPFHMTP--------------MPYDLQG 542

  Fly   952 -DMNSIASGNMMGNGGNTNQHGNRSSYDGFSGNHSDGSGGLPGG-----DGGVNSLDQLNAMEKS 1010
             |.....||:        |||.|.|.....:...||....|...     ......||||:|
  Rat   543 LDFFPFLSGD--------NQHYNTSLLAAAAAAVSDDQDLLHSSRFFPYTSSQMFLDQLSA---- 595

  Fly  1011 LSDQMPHTPHTPGAASHPMTPGGPPSVSSSHNEPISGGTPNANGSGSATNGS--GNNNSSTGHNS 1073
                                 ||..|:            |..|||.|.:|.|  .:|:....|
  Rat   596 ---------------------GGSTSL------------PATNGSSSGSNSSLVSSNSLRESH-- 625

  Fly  1074 PQTPGTPSRMGGGMGGSGSADS 1095
                      |.|:....|||:
  Rat   626 ----------GHGVASRSSADT 637

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tna	NP_001368945.1	Med15	216..>604	CDD:312941	14/77 (18%)
		SP-RING_ZMIZ	792..839	CDD:319705	20/46 (43%)
Pias1	NP_001100299.3	SAP	11..45	CDD:128789
		PINIT	137..285	CDD:405075	32/171 (19%)
		COG5222	<313..428	CDD:227547	38/132 (29%)
		SP-RING_PIAS	332..379	CDD:319704	20/46 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2169
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810