DRSC/TRiP Functional Genomics Resources

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Protein Alignment tna and pias1

DIOPT Version :9

Sequence 1:NP_001368945.1 Gene:tna / 39217 FlyBaseID:FBgn0026160 Length:1186 Species:Drosophila melanogaster
Sequence 2:XP_002932990.1 Gene:pias1 / 100488714 XenbaseID:XB-GENE-486558 Length:648 Species:Xenopus tropicalis


Alignment Length:643 Identity:146/643 - (22%)
Similarity:216/643 - (33%) Gaps:216/643 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   572 NYQHSPVP-----GNP-TPPLTPA-------CSVPYVSPN-----PD---------------IKP 603
            |...|.:|     |:| :.||.|.       ..:|:::.|     ||               |||
 Frog    88 NLSPSSIPQLSYDGHPASSPLMPVSLLPKHELDLPHLASNLHPVHPDVKLQKLPFYDLLDELIKP 152

  Fly   604 ---PMDNSEEMRLT-FPVRDGIILAPFRLLHNLSVSNHVFHLKQNVYNTLMCRNDLELQLK-CFH 663
               ..|||:..:.| |    ...|.| :.:..:|.|..:...|        |...:::||: |..
 Frog   153 TSLASDNSQRFQETCF----AFALTP-QQVQQISSSMDISGTK--------CDFTVQVQLRFCLS 204

  Fly   664 QDDRQMNTNWPHTVTVSANATPLNIERSEKNSTALRPLYL---KAVCQPGR-----NTLQLTASS 720
            :.......::|..:.|..|..|.|:           |.||   |...:|.|     |...|...|
 Frog   205 ETSCPQEDHFPPNLCVKVNGKPCNL-----------PGYLPPTKNGVEPKRPSRPINITSLVRLS 258

  Fly   721 CCCSHLFVLQ--------------LVHRPSVRQVLQTLHKRNLLPLEHSVQKIKRNLSQPEANAG 771
            ....:..|:.              ||.:.|...:||.|..:.:...:||...||..|:     |.
 Frog   259 TTVPNTIVVSWTAEIGRNFSLAVYLVKQLSSAILLQRLRAKGIRNPDHSRALIKEKLT-----AD 318

  Fly   772 PD---ATPQQQQQQGGGQQCAKISLKCPITKSRIRLPARGHECKHVQCFDLEAYLMINSERGSWR 833
            ||   ||..           .::||.||:.|.|:.:|.|...|.|:||||...|:.:|.::.:|.
 Frog   319 PDSEIATTS-----------LRVSLLCPLGKMRLTIPCRSLTCSHLQCFDATLYIQMNEKKPTWV 372

  Fly   834 CPECSKSAITDTLEIDQYIWAILNTLGNSDVDEVIIDSSANWRALQ-----------HNG---GM 884
            ||.|.|.|..:.|.||.....||...  :|.||:......:|..::           :||   |.
 Frog   373 CPVCDKKAPYEHLIIDGLFMEILKCC--TDCDEIQFKEDGSWSPMRSKKEVQEVTTSYNGVDSGC 435

  Fly   885 PNAPPPSNVPSNPSGGSG-----------SNSGN-----------GSVNPTLPVIKQELCDDIAK 927
            .::.....|.||......           |:|..           .|:.|..|:..:.:. ::..
 Frog   436 ISSSVEHQVSSNQQSSKNKKVEVIDLTIDSSSDEEEEEPCPKRSCPSITPASPLSNKGML-NLQH 499

  Fly   928 VMSPGS--TQLPTWDSA---------------QAMSPYNMH--DMNSIASGNMMGNGGNTNQHGN 973
            ..||.|  ..||..||.               ....||::.  |.....||.        |||.|
 Frog   500 QASPISRTPSLPPVDSTYINAPILQDYRHPFHMTHMPYDLQGLDFFPFLSGE--------NQHYN 556

  Fly   974 RSSYDGFSGNHSD------GSGGLPGGDGGVNSLDQLNAMEKSLSDQMPHTPHTPGAASHPMTPG 1032
            .|.....:...|:      .|...|.....: .||||||                          
 Frog   557 TSLLAAAAAAASEEPDLLHSSRFFPYTSSQL-FLDQLNA-------------------------- 594

  Fly  1033 GPPSVSSSHNEPISGGTPNANGSGSATNGS--GNNNSSTGHNSP-QTPGTPSRMGGGM 1087
               |.|||        .|..|||.|.:|.|  .:|:....|::| :.|...|.:.|.|
 Frog   595 ---SASSS--------LPATNGSNSGSNSSLVSSNSLRESHSAPSRGPADSSSLYGIM 641

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tnaNP_001368945.1 Med15 216..>604 CDD:312941 15/67 (22%)
SP-RING_ZMIZ 792..839 CDD:319705 20/46 (43%)
pias1XP_002932990.1 SAP 11..45 CDD:128789
PINIT 136..279 CDD:373014 32/166 (19%)
COG5222 <312..427 CDD:227547 38/132 (29%)
SP-RING_PIAS 331..378 CDD:319704 20/46 (43%)
SP-RING finger 334..376 CDD:319704 17/41 (41%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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