Protein Alignment NijA and NINJ2

DIOPT Version :10

• Sequence 1: NP_996040.1
• Gene: NijA / 39215
• FlyBaseID: FBgn0036101
• Length: 245
• Species: Drosophila melanogaster
• Sequence 2: NP_057617.3
• Gene: NINJ2 / 4815
• HGNCID: 7825
• Length: 142
• Species: Homo sapiens
• Alignment Length: 122
• Identity: 41/122 - (33%)
• Similarity: 66/122 - (54%)
• Gaps: 8/122 - (6%)

  Fly   109 PGYNGPGFVTINGVETPIPDVNAYQHKKTLAQGMMDLALLSANANQLRYVLETSSQHPYFYPSLL 173
            ||.:.|....||        :|.|..||::|:.|:|:||..:||.:|:.|||......|:...:.
Human    12 PGSSDPRSQPIN--------LNHYATKKSVAESMLDVALFMSNAMRLKAVLEQGPSSHYYTTLVT 68

  Fly   174 FISLSIIFQIAVGVGLILNGQYNIKNGHDICRANRINNYTVSGIFIVTVVNVLISAF 230
            .||||::.|:.:||.|::..:.|:.......|.|::||.....:|...|:||.|:||
Human    69 LISLSLLLQVVIGVLLVVIARLNLNEVEKQWRLNQLNNAATILVFFTVVINVFITAF 125

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NijA	NP_996040.1	Ninjurin	129..230	CDD:461482	34/100 (34%)
NINJ2	NP_057617.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21		3/8 (38%)
		Ninjurin	24..125	CDD:461482	34/100 (34%)
		Helix alpha1. /evidence=ECO:0000269|PubMed:39667936, ECO:0007744|PDB:8SZB	25..37		5/11 (45%)
		Helix alpha2. /evidence=ECO:0000269|PubMed:39667936, ECO:0007744|PDB:8SZB	38..57		9/18 (50%)