Protein Alignment NijA and Ninj1

DIOPT Version :9

• Sequence 1: NP_996040.1
• Gene: NijA / 39215
• FlyBaseID: FBgn0036101
• Length: 245
• Species: Drosophila melanogaster
• Sequence 2: NP_036999.1
• Gene: Ninj1 / 25338
• RGDID: 3179
• Length: 152
• Species: Rattus norvegicus
• Alignment Length: 144
• Identity: 54/144 - (37%)
• Similarity: 85/144 - (59%)
• Gaps: 5/144 - (3%)

  Fly    99 NGGRRP-SFSFPGYNGPGFVTINGVETPIPDVNAYQHKKTLAQGMMDLALLSANANQLRYVLETS 162
            ||..|| |...|..:.|.:...|   .|| :||.|.:||:.|:.|:|:|||.|||:||:.|:|..
  Rat    11 NGDLRPGSPGSPDASPPRWGLRN---RPI-NVNHYANKKSAAESMLDIALLMANASQLKAVVEQG 71

  Fly   163 SQHPYFYPSLLFISLSIIFQIAVGVGLILNGQYNIKNGHDICRANRINNYTVSGIFIVTVVNVLI 227
            ::..:|.|.::.||:|::.||.|||.||...:|::.|.....:.:.:||.....:||:.|||:.|
  Rat    72 NEFAFFVPLVVLISISLVLQIGVGVLLIFLVKYDLNNPAKHAKLDFLNNLATGLVFIIVVVNIFI 136

  Fly   228 SAFTVDRDTVPALP 241
            :||.|.:..:...|
  Rat   137 TAFGVQKPVMDVAP 150

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NijA	NP_996040.1	Ninjurin	130..230	CDD:282740	39/99 (39%)
Ninj1	NP_036999.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..30		7/18 (39%)
		N-terminal adhesion motif. /evidence=ECO:0000269|PubMed:33028854	26..37		4/14 (29%)
		Ninjurin	39..139	CDD:398538	39/99 (39%)
		Required to induce plasma membrane rupture. /evidence=ECO:0000250|UniProtKB:O70131	40..69		15/28 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	86	1.000	Domainoid score	I7960
eggNOG	1	0.900	-	-		E1_2BDMP
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1560683at2759
OrthoFinder	1	1.000	-	-		FOG0001262
OrthoInspector	1	1.000	-	-		mtm8945
orthoMCL	1	0.900	-	-		OOG6_103284
Panther	1	1.100	-	-	O	PTHR12316
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.780