DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11811 and dlg5

DIOPT Version :9

Sequence 1:	NP_648408.1	Gene:	CG11811 / 39213	FlyBaseID:	FBgn0036099	Length:	233	Species:	Drosophila melanogaster
Sequence 2:	XP_004916076.1	Gene:	dlg5 / 779611	XenbaseID:	XB-GENE-978275	Length:	1971	Species:	Xenopus tropicalis

Alignment Length:	190	Identity:	43/190 - (22%)
Similarity:	81/190 - (42%)	Gaps:	35/190 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 KKMTAPGPRPLVLCGP-SGSGKSTLLKRLFAEFPSTFGFSISHTTRKPREGEEHGVHYYFVERPE 91
            :::....|||:::.|| ..:.|..|:|    |.|..|       .|.|.|          |.:..
Frog  1784 QRVDCTSPRPVLILGPLVDAVKDMLVK----ESPGKF-------CRCPLE----------VMKAS 1827

  Fly    92 MEAAIAGDE---FIETAEFTGNLYGTSKAAVREIQAQGRVCILDIEQKGVEQIKRTDLNPILIF- 152
            .:|...|.:   ||:....:|:...|:.|:::||..:...|:|||....:|::....:.||::|
Frog  1828 QQAIERGVKDCLFIDYKRRSGHFDVTTVASIKEITEKDCHCLLDIAPHAIERLHSVHIYPIVLFI 1892

  Fly   153 --NNPPSIKELERRLRKRGSETEESLSKRLNAA-QVELDYG------LTPGNFHKIINNV 203
              .:...|||.:..:..|...|::...::...| ::|.:|.      :..|....|.|.:
Frog  1893 RYKSTKQIKEQKDPIFLRDKVTQKHSKEQFETAHKIEQEYSKYFTAVIQGGALFSICNQI 1952

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11811	NP_648408.1	Guanylate_kin	34..219	CDD:279019	43/184 (23%)
CG11811	NP_648408.1	guanyl_kin	36..216	CDD:213788	42/182 (23%)
dlg5	XP_004916076.1	CARD	9..88	CDD:260018
		Takusan	127..213	CDD:368141
		Smc	<136..544	CDD:224117
		COG4372	443..>672	CDD:226809
		PDZ_signaling	697..784	CDD:238492
		PDZ_signaling	798..867	CDD:238492
		PDZ	1395..1477	CDD:214570
		dbPDZ_assoc	1475..1554	CDD:374667
		PDZ	1554..1633	CDD:214570
		SH3_DLG5	1649..1711	CDD:212794
		GuKc	1784..1960	CDD:214504	43/190 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910