DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11811 and Mpp7

DIOPT Version :9

Sequence 1:	NP_648408.1	Gene:	CG11811 / 39213	FlyBaseID:	FBgn0036099	Length:	233	Species:	Drosophila melanogaster
Sequence 2:	XP_011245327.1	Gene:	Mpp7 / 75739	MGIID:	1922989	Length:	601	Species:	Mus musculus

Alignment Length:	192	Identity:	67/192 - (34%)
Similarity:	101/192 - (52%)	Gaps:	18/192 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 RPLVLCGPSGSGKSTLLKRLFAEFPSTFGFSISHTTRKPREGEEHGVHYYFVERPEMEAAIAGDE 100
            |.:||.||.|.|.:.|.::|.......:|..:.||||..|..|..||.|.|:.:...|..:..::
Mouse   394 RLIVLVGPVGVGLNELKRKLLMSDAQHYGVIVPHTTRARRSQESDGVEYIFISKHLFETDVQNNK 458

  Fly   101 FIETAEFTGNLYGTSKAAVREIQAQGRVCILDIEQKGVEQIKRTDLNPILIFNNPPSIKELERRL 165
            |||..|:..|.||||..:||.:.|:.:||:||::...|:.::..:..|.:||..||||:.| |..
Mouse   459 FIEYGEYKNNYYGTSIDSVRSVLAKNKVCLLDVQPHTVKHLRTLEFKPYVIFIKPPSIERL-RET 522

  Fly   166 RK----------RGSE---TEESLSKRLNAAQV-ELDYGLTPGNFHKIINNVDIDVAYEEFR 213
            ||          :|:.   |||...:.:.:||: |..||..   |.|||.|.|:.||:.|.:
Mouse   523 RKNAKIISSRDDQGTAKPFTEEDFQEMIKSAQIMESQYGHL---FDKIIINDDLTVAFNELK 581

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11811	NP_648408.1	Guanylate_kin	34..219	CDD:279019	67/192 (35%)
CG11811	NP_648408.1	guanyl_kin	36..216	CDD:213788	67/192 (35%)
Mpp7	XP_011245327.1	L27	16..68	CDD:197794
		L27	75..125	CDD:197794
		PDZ_signaling	137..217	CDD:238492
		SH3_MPP7	232..292	CDD:212966
		GuKc	403..588	CDD:214504	62/183 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0194
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810