DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11811 and Mpp4

DIOPT Version :9

Sequence 1:	NP_648408.1	Gene:	CG11811 / 39213	FlyBaseID:	FBgn0036099	Length:	233	Species:	Drosophila melanogaster
Sequence 2:	XP_038940071.1	Gene:	Mpp4 / 58808	RGDID:	620016	Length:	636	Species:	Rattus norvegicus

Alignment Length:	195	Identity:	58/195 - (29%)
Similarity:	98/195 - (50%)	Gaps:	32/195 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 KKMTAPGPRPLVLCGPSGSGKSTLLKRLFAEFPSTFGFSISHTTRKPREGEEHGVHYYFVERPEM 92
            ::..|...|.:||.||||.|.:.|.::|....||.|..::.||||.|:..|..|..|::|.|...
  Rat   420 QRQPADKHRLIVLVGPSGVGVNELRRQLIGCNPSCFQSAVPHTTRSPKSYEMDGREYHYVSRETF 484

  Fly    93 EAAIAGDEFIETAEFTGNLYGTSKAAVREIQAQGRVCILDIEQKGVEQIKRTDLNPILIFNNPPS 157
            |:.:.|...:|..|:.|:|||||..||..:..:|::|::|:|.:.::..:..:|.|.:||..|||
  Rat   485 ESLMYGHRMLEFGEYKGHLYGTSVNAVLAVLDEGKICVMDLEPQDIQLARTRELKPYVIFIKPPS 549

  Fly   158 IKELERRLRKRGSETEESLSKRLNAAQVELDYGLTPGNFHKIINNVDIDVAYEEFRNFVVQELKE 222
            :..:..              .|.||               |||.:..:|:   :|::..:||::|
  Rat   550 MSSMRH--------------SRRNA---------------KIITDYFVDM---KFKDEDLQEMEE 582

Fly 223 222
Rat 583 582

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11811	NP_648408.1	Guanylate_kin	34..219	CDD:279019	54/184 (29%)
CG11811	NP_648408.1	guanyl_kin	36..216	CDD:213788	54/179 (30%)
Mpp4	XP_038940071.1	L27	<79..114	CDD:197794
		L27	124..171	CDD:197794
		PDZ_signaling	184..263	CDD:238492
		SH3_MPP4	277..337	CDD:212967
		Guanylate_kin	428..618	CDD:395500	57/187 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0194
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810